Evidence map›Paper›PMID 24057105›Full record

ReviewCurrent genetics2013

The emergence of lipid droplets in yeast: current status and experimental approaches.

Maja Radulovic, Oskar Knittelfelder, Alvaro Cristobal-Sarramian, Dagmar Kolb, Heimo Wolinski, Sepp D Kohlwein

Abstract readReview
In one paragraph

Review in Current genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

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  15. Recovery of Fungal Cells from Air Samples: a Tale of Loss and Gain.Applied and environmental microbiology · 2019
    Article
  16. The nutritional requirements ofGenes & nutrition · 2019
    Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maja RadulovicInstitute of Molecular Biosciences, University of Graz, Humboldtstrasse 50/II, 8010, Graz, Austria.
Oskar Knittelfelder
Alvaro Cristobal-Sarramian
Dagmar Kolb
Heimo Wolinski
Sepp D Kohlwein

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 'discovery' of lipid droplets as a metabolically highly active subcellular organelle has sparked great scientific interest in its research in recent years. The previous view of a rather inert storage pool of neutral lipids--triacylglycerol and sterols or steryl esters--has markedly changed. Driven by the endemic dimensions of lipid-associated disorders on the one hand, and the promising biotechnological application to generate oils ('biodiesel') from single-celled organisms on the other, multiple model organisms are exploited in basic and applied research to develop a better understanding of biogenesis and metabolism of this organelle. This article summarizes the current status of LD research in yeast and experimental approaches to obtain insight into the regulatory and structural components driving lipid droplet formation and their physiological and pathophysiological roles in lipid homeostasis.

Indexed as

Biosynthetic PathwaysCytosolEstersHomeostasisLipid MetabolismLipidsMicroscopy, Electron, TransmissionMicroscopy, FluorescenceResearchSpectrum Analysis, RamanSterolsTriglyceridesYeastsEstersLipidsSterolsTriglycerides

Identifiers

PMID24057105
PMCPMC3824194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.