ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2014
Analysis of 101 patients with severe to profound sudden unilateral hearing loss treated with explorative tympanotomy and sealing of the round window membrane.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Salvage treatment strategies for refractory sudden sensorineural hearing loss-a comprehensive review and meta-analysis with practical recommendations.Frontiers in neurology · 2025Pooled it
- Current Role of the Nonsteroid Treatment of Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL): A Narrative Review.Journal of clinical medicine · 2025Review
- Safety and audiological outcome in a case series of tertiary therapy of sudden hearing loss with a biodegradable drug delivery implant for controlled release of dexamethasone to the inner ear.Frontiers in neuroscience · 2022Article
- Article
- Prognostic factors regarding the hearing outcome in severe to profound sudden sensorineural hearing loss treated by tympanotomy and sealing of labyrinthine windows after ineffective systemic corticosteroid application.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Article
- Inpatient treatment of patients with idiopathic sudden sensorineural hearing loss: a population-based healthcare research study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Article
- Predictors of hearing recovery in patients with severe sudden sensorineural hearing loss.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2017Article
- Diagnostics and therapy of sudden hearing loss.GMS current topics in otorhinolaryngology, head and neck surgery · 2017Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this retrospective study was to evaluate the effect of sealing of the round window membrane in patients with severe to profound unilateral sudden sensorineural hearing loss (SSNHL). 101 Patients with unilateral SSNHL were treated with tympanotomy and sealing of the round window membrane if hearing did not improve after conservative treatment. Preoperative and postoperative pure tone audiograms after removal of the ear packing were evaluated. A 4-PTA (pure tone audiometry) was used as reference value. The improvement of 4-PTA was analysed; in addition, recovery was evaluated using Siegel's criteria. Mean initial hearing threshold was 101.1 dB. Eighty-one patients had a hearing threshold of 80 dB or more. The average improvement at the time of ear packing was 21.7 dB and a further average recovery of 13.4 dB was recorded in the follow-up. Patients who underwent rapid tympanotomy within 5 days showed a significantly better hearing improvement than patients with delayed tympanotomy (26.9 vs. 14.0 dB, p < 0.02). Age was significantly correlated with the degree of hearing improvement. There was no significant difference of recovery between patients with detected lesions of the round window membrane and those without. Concomitant vertigo and tinnitus showed no significant effect on recovery. Tympanotomy and sealing of the round window membrane is effective in the treatment of severe to profound SSNHL. There is evidence that early surgery performed within 5 days is more effective than later surgery. The existence of a detectable lesion of the round window membrane has no significant influence on recovery.
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