ArticleEuropean heart journal2014
Symptoms of anxiety and depression and risk of acute myocardial infarction: the HUNT 2 study.
Article in European heart journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Association of Depression with Subclinical Coronary Atherosclerosis: a Systematic Review.Journal of cardiovascular translational research · 2021Pooled it
- Sex- and Gender-Stratified Risks of Psychological Factors for Incident Ischemic Heart Disease: Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2019Pooled it
- Depression and the Risk of Myocardial Infarction and Coronary Death: A Meta-Analysis of Prospective Cohort Studies.Medicine · 2016Pooled it
- Blueprint 2: A self-directed mobile adaptive coping skills intervention to improve psychological distress symptoms among cardiorespiratory failure survivors study protocol.Contemporary clinical trials · 2026Article
- Depression, Anxiety, and Bipolar Disorder and Atherosclerosis.Current atherosclerosis reports · 2026Review
- Article
- Association between plant-based diets and depressive symptoms among Chinese middle-aged and older adults.NPJ science of food · 2025Article
- The therapeutic effects ofGut microbiome (Cambridge, England) · 2025Review
- Anxiety, a significant risk factor for coronary artery disease: what is the best index.BMC psychiatry · 2024Article
- Article
- Anxiety and depression symptoms, albuminuria and risk of acute myocardial infarction in the Norwegian HUNT cohort study.BMC cardiovascular disorders · 2022Article
- Article
- Article
- Association of Symptoms of Depression With Cardiovascular Disease and Mortality in Low-, Middle-, and High-Income Countries.JAMA psychiatry · 2020Article
- Atopic Eczema in Adulthood and Risk of Depression and Anxiety: A Population-Based Cohort Study.The journal of allergy and clinical immunology. In practice · 2020Article
- Work disability patterns before and after incident acute myocardial infarction and subsequent risk of common mental disorders: A Swedish cohort study.Scientific reports · 2019Article
- Symptoms of Depression and Risk of Abdominal Aortic Aneurysm: A HUNT Study.Journal of the American Heart Association · 2019Article
- Updated Geriatric Cardiology Guidelines of the Brazilian Society of Cardiology - 2019.Arquivos brasileiros de cardiologia · 2019Article
- Traumatic Events, Personality and Psychopathology in Takotsubo Syndrome: A Systematic Review.Frontiers in psychology · 2019Review
- Does Moderate Drinking Increase the Risk of Atrial Fibrillation? The Norwegian HUNT (Nord-Trøndelag Health) Study.Journal of the American Heart Association · 2017Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe nature of the association of depression and anxiety with risk for acute myocardial infarction (AMI) remains unclear. We aimed to study the prospective association of single and recurrent self-reported symptoms of anxiety and depression with a risk of AMI in a large Norwegian population based cohort. METHODS AND
resultsIn the second wave of the Nord-Trøndelag Health Study (HUNT2, 1995-97) baseline data on anxiety and depression symptoms, sociodemographic variables, health status including cardiovascular risk factors and common chronic disorders were registered for 57,953 adult men and women free of cardiovascular disease. The cohort was followed up during a mean (SD) 11.4 (2.9) years for a first AMI from baseline through 2008. A total of 2111 incident AMIs occurred, either identified at hospitals or by the National Cause of Death Registry. The multi-adjusted hazard ratios were 1.31 (95% CI 1.03-1.66) for symptoms of depression and 1.25 (CI 0.99-1.57) for anxiety. Two episodes of mixed symptoms of anxiety and depression (MSAD), reported 10 years apart, increased the risk for AMI by 52% (11-108%). After exclusion of the first 5 years of follow-up, the association of depression symptoms with AMI risk was attenuated. Relative risk for AMI with anxiety symptoms and MSAD weakened when participants with chronic disorders were excluded.
conclusionSelf-reported symptoms of depression and anxiety, especially if recurrent, were moderately associated with the risk of incident AMI. We had some indications that these associations might partly reflect reverse causation or confounding from common chronic diseases.
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