Evidence map›Paper›PMID 24056732›Full record

ReviewChemical Society reviews2014

Protein induced fluorescence enhancement (PIFE) for probing protein-nucleic acid interactions.

Helen Hwang, Sua Myong

Open access · greenAbstract readReview
In one paragraph

Review in Chemical Society reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 243 citations in OpenAlex.

  1. Quantifying Label-Free Protein-RNA Binding Using Microscale Thermophoresis.Methods in molecular biology (Clifton, N.J.) · 2027
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  15. Review
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  17. Protection of the Telomeric Junction by the Shelterin Complex.Journal of the American Chemical Society · 2024
    Article
  18. Article
  19. Protection of the Telomeric Junction by the Shelterin Complex.bioRxiv : the preprint server for biology · 2024
    Article
  20. Binding Behavior of Human Hepatoma-Derived Growth Factor onThe journal of physical chemistry. B · 2024
    Article

64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Helen HwangBioengineering Department, University of Illinois at Urbana-Champaign, USA. smyong@illinois.edu.
Sua Myong
University of Illinois Urbana-Champaign · US

Funding

The Role of Structural Dynamics on Telomeric End AccessibilityF30CA174323 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HWANG, HELEN · 2013 to 2015
$135k
NCI NIH HHS F30 CA174323
6 · The paper itself

Abstract

Single molecule studies of protein-nucleic acid interactions shed light on molecular mechanisms and kinetics involved in protein binding, translocation, and unwinding of DNA and RNA substrates. In this review, we provide an overview of a single molecule fluorescence method, termed "protein induced fluorescence enhancement" (PIFE). Unlike FRET where two dyes are required, PIFE employs a single dye attached to DNA or RNA to which an unlabeled protein is applied. We discuss both ensemble and single molecule studies in which PIFE was utilized.

Indexed as

AnimalsEquipment DesignHumansMicroscopy, FluorescenceNucleic AcidsProtein BindingProteinsSpectrometry, FluorescenceNucleic AcidsProteins

Identifiers

PMID24056732
PMCPMC4142350
OpenAlexW2111814713

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.