ArticleAnnals of surgical oncology2013
Prognosis of solitary fibrous tumors: a multicenter study.
Article in Annals of surgical oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
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Who cites it
74 citing papers in PubMed, 164 citations in OpenAlex.
- Construction and Characterization of Paired Patient-Derived Cell Models for Solitary Fibrous Tumors (SFTs).Cancers · 2026Article
- Cytologic and Histologic Findings of Extrapleural Solitary Fibrous Tumor: Report of Two Cases.Diagnostic cytopathology · 2026Article
- Article
- A Rare Metastatic Fibrous Tumor: Review of Literature With a Case Report.JTO clinical and research reports · 2025Article
- Malignant solitary fibrous tumor of the kidney with extracapsular extension beyond the renal capsule: An extremely rare Uro-oncological surgical case and diagnostic challenge.Urology case reports · 2025Article
- Establishment and characterization of NCC-SFT1-C1: a novel patient-derived cell line of solitary fibrous tumor.Human cell · 2025Article
- A rare case of a giant pulmonary solitary fibrous tumor: Diagnostic and therapeutic challenges in the absence of malignancy.Respiratory medicine case reports · 2025Article
- Solitary fibrous tumor of the Pelvic cavity: A rare entity with review of literature.Radiology case reports · 2024Article
- Solitary fibrous tumor of the parapharyngeal space: report of 2 cases and a literature review.Oral and maxillofacial surgery · 2024Review
- A Giant Malignant Solitary Fibrous Tumor of the Pancreas: A Case Report and Review of the Literature.Cureus · 2024Article
- Repeated Radiation Therapy of Recurrent Solitary Fibrous Tumors of the Brain: A Medical Case History Over 20 Years.Advances in radiation oncology · 2024Article
- Exploring Solitary Fibrous Tumors at a Tertiary Cancer Center: Clinicopathological and Immunomorphologic Profile.Cureus · 2024Article
- Risk factors for recurrent disease after resection of solitary fibrous tumor: a systematic review.Frontiers in surgery · 2024Review
- Giant intrapulmonary solitary fibrous tumor with signs of malignancy.Journal of surgical case reports · 2024Article
- Solitary fibrous tumor in the retroperitoneum: A case report.International journal of surgery case reports · 2024Article
- Review
- Comprehensive analysis reveals potential therapeutic targets and an integrated risk stratification model for solitary fibrous tumors.Nature communications · 2023Article
- Solitary fibrous tumor in the temporalis muscle: a case report and literature review.Archives of craniofacial surgery · 2023Article
- Primary retroperitoneal solitary fibrous tumor: A case report.Clinical case reports · 2023Article
- Diagnosis and management of an extremely rare solitary fibrous tumor in the retropubic space of Retzius: A case report.International journal of surgery case reports · 2023Article
14 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSolitary fibrous tumors (SFTs) are rare mesenchymal tumors, and data regarding outcome and prognostic factors are scarce. We report the outcome and analysis of prognostic factors of a retrospective multicenter cohort study for patients treated for SFTs.
methodsRetrospective analysis was performed of patients treated for SFTs between 1995 and 2012. Clinical and histopathological features were analyzed for prognostic value. Endpoints were set at local recurrence, metastasis formation, or death. Survival was analyzed using Kaplan-Meier and Cox proportional hazards analyses.
resultsA total of 81 patients underwent surgical resection of a SFT with curative intent. During follow-up, 21 patients developed distant metastases, while 18 patients developed local recurrence. The 5-year overall survival was 84 %. The local recurrence rate and the metastasis rate at 5 years were 29 and 34 %, respectively. Of all factors analyzed, positive resection margin significantly correlated with local recurrence [hazard ratio (HR) 4.8; 95 % confidence interval (95 % CI) 1.5-14.9]. Tumor size >10 cm (HR 4.4; 95 % CI 1.7-11.5) and high mitosis rate (HR 3.3; 95 % CI 1.06-10.3) significantly correlated with higher incidence of metastases. The combination of tumors >10 cm and high mitosis rate significantly correlated with higher incidence of metastases (HR 4.8; 95 % CI 1.4-16.2) and showed a trend toward worse overall survival (HR 5.7; 95 % CI 0.95-34.7).
conclusionsA substantial portion of patients with a SFT developed local recurrence or metastases. Local recurrence is significantly higher in patients with positive resection margins; metastasis frequency is significantly higher in patients with tumors >10 cm and tumors with a high mitosis rate.
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