Evidence map›Paper›PMID 24052233›Full record

ArticleMolecular biology reports2013

Characterization of microRNA expression profiles in 3T3-L1 adipocytes overexpressing C10orf116.

Jie Qiu, Xiao-guang Zhou, Xiao-yu Zhou, Chun Zhu, Chun-mei Shi, Chen-bo Ji, Rui Cheng, Yong Li, Xi-rong Guo

Registry-linked trialAbstract read
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In one paragraph

Article in Molecular biology reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07701434 ("The Effect of the Cord Clamping Bundle at Birth Developed With the Delphi Method on Maternal and Newborn Outcomes"), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.1field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07701434 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

"The Effect of the Cord Clamping Bundle at Birth Developed With the Delphi Method on Maternal and Newborn Outcomes"

TypeinterventionalSponsorElif MARANGOZRan2026 to 2026Enrolled100ConditionsEffects of a Cord Clamping Bundle on Maternal and Neonatal OutcomesArmsCord Clamping Bundle, Routine Cord Clamping Care
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  3. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jie QiuDepartment of Newborn Infants, Nanjing Children's Hospital of Nanjing Medical University, Nanjing, 210008, China, jieqiu.nj@hotmail.com.
Xiao-guang Zhou
Xiao-yu Zhou
Chun Zhu
Chun-mei Shi
Chen-bo Ji
Rui Cheng
Yong Li
Xi-rong Guo
Second Affiliated Hospital of Nanjing Medical University · CNNanjing Maternity and Child Health Care Hospital · CNNanjing Medical University · CNNanjing Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our data in the previous report demonstrated that C10orf116 (AFRO) is an adipocyte lineage-specific nuclear factor that can modulate the master adipogenesis transcription factors early during differentiation. However, more precise functional properties of this gene need to be clarified and await further investigation. Therefore, in this study, we performed an expression profile of cellular MicroRNAs (miRNAs) in the C10orf116 overexpression 3T3-L1 adipocytes and performed target prediction and functional enrichment of the differentially expressed miRNAs. Our study identified 34 miRNAs up-regulated in the 3T3-L1 adipocytes stably overexpressing C10orf116, whereas 43 miRNAs up-regulated in the control cells. The target genes of differentially expressed miRNAs were found to be involved in multiple signalling pathways, such as Wnt, TGF-beta, MAPK, Jak-STAT, insulin signalling pathway, et al. Our data provided novel information for the identification of C10orf116.

Indexed as

Gene ExpressionTranscriptome3T3-L1 CellsAdipocytesAdipogenesisAnimalsGene Expression RegulationLipid MetabolismMiceMicroRNAsNuclear ProteinsReproducibility of ResultsTransfectionADIRF protein, humanMicroRNAsNuclear Proteins

Identifiers

PMID24052233
OpenAlexW2062745878

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.