ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2014
The impact of computed tomography slice thickness on the assessment of stereotactic, 3D conformal and intensity-modulated radiotherapy of brain tumors.
Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 13 citations in OpenAlex.
- Principles of Stereotactic Surgery.Operative neurosurgery (Hagerstown, Md.) · 2025Review
- Gross target volume contouring in canine extra-axial brain tumors: Effects of magnetic resonance image slice thickness and time between subsequent image sets.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2025Article
- Assessing the accuracy of computed tomography in detecting bony invasion and thickness of squamous cell carcinoma of the scalp.The neuroradiology journal · 2021Article
- Assessment of biological dosimetric margin for stereotactic body radiation therapy.Journal of applied clinical medical physics · 2020Article
- Impact of CT slice thickness on volume and dose evaluation during thoracic cancer radiotherapy.Cancer management and research · 2018Article
- A simple method of evaluating margin-growing accuracy in image-guided radiation therapy.The British journal of radiology · 2016Article
- The effect of slice thickness on target and organs at risk volumes, dosimetric coverage and radiobiological impact in IMRT planning.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2016Article
- What is the best way to evaluate clinical target volume for radiotherapy of brain tumors?CNS oncology · 2013Article
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5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate radiotherapy treatment planning accuracy by varying computed tomography (CT) slice thickness and tumor size.
methodsCT datasets from patients with primary brain disease and metastatic brain disease were selected. Tumor volumes ranging from about 2.5 to 100 cc and CT scan at different slice thicknesses (1, 2, 4, 6 and 10 mm) were used to perform treatment planning (1-, 2-, 4-, 6- and 10-CT, respectively). For any slice thickness, a conformity index (CI) referring to 100, 98, 95 and 90 % isodoses and tumor size was computed. All the CI and volumes obtained were compared to evaluate the impact of CT slice thickness on treatment plans.
resultsThe smallest volumes reduce significantly if defined on 1-CT with respect to 4- and 6-CT, while the CT slice thickness does not affect target definition for the largest volumes. The mean CI for all the considered isodoses and CT slice thickness shows no statistical differences when 1-CT is compared to 2-CT. Comparing the mean CI of 1- with 4-CT and 1- with 6-CT, statistical differences appear only for the smallest volumes with respect to 100, 98 and 95 % isodoses-the CI for 90 % isodose being not statistically significant for all the considered PTVs.
conclusionsThe accuracy of radiotherapy tumor volume definition depends on CT slice thickness. To achieve a better tumor definition and dose coverage, 1- and 2-CT would be suitable for small targets, while 4- and 6-CT are suitable for the other volumes.
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