ArticleInternational orthopaedics2013
Remission rate of implant-related infections following revision surgery after fractures.
Article in International orthopaedics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03602209 (Short vs. Long Antibiotic Treatment of Implant-free Osteoarticular Infections), which is not on this map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Short vs. Long Antibiotic Treatment of Implant-free Osteoarticular Infections
Who cites it
20 citing papers in PubMed, 54 citations in OpenAlex.
- Short Against Long Antibiotic Therapy for Infected Orthopaedic Sites-2nd Interim Analysis of the SALATIO Trials.Journal of clinical medicine · 2026Article
- Biofilm Formation and Antibiotic Resistance in Orthopaedic Implant Infections: A Molecular Analysis of icaA, icaD, and mecA Genes in an Indian Cohort.Indian journal of orthopaedics · 2026Article
- Analyzing risk factors for treatment failure in fracture-related infection.Archives of orthopaedic and trauma surgery · 2023Article
- Article
- Epidemiology and outcomes of bone and joint infections in solid organ transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022Article
- A systematic review of phage therapy applied to bone and joint infections: an analysis of success rates, treatment modalities and safety.EFORT open reviews · 2021Review
- Risk factors associated with infection recurrence of posttraumatic osteomyelitis treated with Ilizarov bone transport technique-a retrospective study of 149 cases.BMC musculoskeletal disorders · 2021Article
- Osteoarticular infections: a specific program for older patients?Aging clinical and experimental research · 2021Review
- Article
- Optimization of the antibiotic management of diabetic foot infections: protocol for two randomized controlled trials.Trials · 2020Article
- Duration of antibiotic treatment and risk of recurrence after surgical management of orthopaedic device infections: a multicenter case-control study.BMC musculoskeletal disorders · 2019Article
- Changing perioperative prophylaxis during antibiotic therapy and iterative debridement for orthopedic infections?PloS one · 2019Article
- Intramedullary reaming modality for management of postoperative long bone infection: a prospective randomized controlled trial in 44 patients.Patient safety in surgery · 2019Article
- Should antibiotic prophylaxis before orthopedic implant surgery depend on the duration of pre-surgical hospital stay?Antimicrobial resistance and infection control · 2018Article
- Clinical and epidemiological differences between implant-associated and implant-free orthopaedic infections.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2017Article
- Which Orthopaedic Patients Are Infected with Gram-negative Non-fermenting Rods?Journal of bone and joint infection · 2017Article
- Predisposing factors for recurrence of chronic posttraumatic osteomyelitis: a retrospective observational cohort study from a tertiary referral center in Brazil.Patient safety in surgery · 2017Article
- Polymicrobial infections reduce the cure rate in prosthetic joint infections: outcome analysis with two-stage exchange and follow-up ≥two years.International orthopaedics · 2016Article
- Variables associated with remission in spinal surgical site infections.Journal of spine surgery (Hong Kong) · 2016Article
- Increased risk of joint failure in hip prostheses infected with Staphylococcus aureus treated with debridement, antibiotics and implant retention compared to Streptococcus.International orthopaedics · 2015Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn contrast to a large amount of epidemiological data regarding the incidence of implant infections after fracture management, surprisingly few have been published concerning the success of their treatment.
methodsThis was a single-centre cohort study at Geneva University Hospitals from 2000 to 2012 investigating the remission rates of orthopaedic implant infections after fracture repair and associated variables.
resultsA total of 139 episodes were included: There were 51 women (37%) and 28 immunosuppressed (20%) patients with a median age and American Society of Anaesthesiologists (ASA) score of 51 years and 2 points, respectively. The infected implants were plates (n = 75, 54 %), nails (24, 17%), wires (20), screws (10), cerclage cables or wires (3), hip screws (4) or material for spondylodesis (3). A pathogen was identified in 135 (97%) cases, including Staphylococcus aureus (73, 52%), coagulase-negative staphylococci (20), streptococci (7) and 19 Gram-negative rods. All patients underwent antibiotic treatment, and 128 (92%) remained in remission at a median follow-up time of 2.6 years (range one to 13 years). In multivariate logistic regression analysis, the plate infections were significantly associated with lower remission rates [65/75, 87%, odds ratio (OR) 0.1, 95% confidence interval (CI) 0.01-0.90]. No associations were found for gender, age, immune status, ASA score, additional surgical interventions (OR 0.4, 95% CI 0.1-4.1) or duration of antibiotic treatment (OR 1.0, 95% CI 0.98-1.01).
conclusionsAmong all infected and removed orthopaedic implants, plates were associated with slightly lower remission rates, while the overall treatment success exceeded 90%. The duration of antibiotic therapy did not alter the outcome.
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