Evidence map›Paper›PMID 24051382›Full record

ArticleThe Journal of clinical investigation2013

Opening lines of communication in the distal nephron.

Thomas R Kleyman, Lisa M Satlin, Kenneth R Hallows

Open access · bronzeAbstract readComment
In one paragraph

Article in The Journal of clinical investigation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. High Salt Activates CD11cHypertension (Dallas, Tex. : 1979) · 2019
    Article
  6. Review
  7. Review
  8. Epithelial NaAnnual review of physiology · 2018
    Review
  9. Article
  10. Review
  11. Collecting duct intercalated cell function and regulation.Clinical journal of the American Society of Nephrology : CJASN · 2015
    Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Thomas R Kleyman
Lisa M Satlin
Kenneth R Hallows

Funding

Regulation of K and H secretion by intercalated cellsR01DK038470 · NIDDK · YESHIVA UNIVERSITY · PI HUGHEY, REBECCA P, KLEYMAN, THOMAS R · 1994 to 2022
$7.7M
Biomechanical Regulation of Renal Ion TransportersR37DK051391 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2006 to 2015
$3.2M
Sodium Channel BiogenesisR01DK065161 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HUGHEY, REBECCA P, KLEYMAN, THOMAS R · 2004 to 2013
$2.8M
Mechanisms and Relevance of Sodium Transport Regulation by AMPKR01DK075048 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HALLOWS, KENNETH R · 2007 to 2015
$2.5M
SODIUM CHANNELS IN THE MAMMALIAN URINARY BLADDERR01DK051391 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R. · 1996 to 2005
$1.5M
Sodium Channel BiogenesisR56DK065161 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HUGHEY, REBECCA P, KLEYMAN, THOMAS R · 2008 to 2008
$226k
RENAL INTERCALATED CELL REGULATION AND DIFFERENTIATIONR29DK038470 · NIDDK · YESHIVA UNIVERSITY · PI SATLIN, LISA M. · 1986 to 1990
–
NIDDK NIH HHS DK038470NIDDK NIH HHS DK065161NIDDK NIH HHS DK075048NIDDK NIH HHS R01 DK038470NIDDK NIH HHS R01 DK051391NIDDK NIH HHS R01 DK065161NIDDK NIH HHS R01 DK075048NIDDK NIH HHS R37 DK051391NIDDK NIH HHS R56 DK065161
6 · The paper itself

Abstract

The distal nephron is composed of two main cell types: principal cells and intercalated cells. These cells have distinct morphologic features that allow them to be readily distinguished by light microscopy, as well as distinct suites of proteins that facilitate cell-specific transport properties. In this issue of the JCI, Gueutin and colleagues describe a new mechanism by which β-intercalated cells, via release of ATP and prostaglandin E2 (PGE2), influence the activity of transporters in principal cells.

Indexed as

Water-Electrolyte BalanceAnimalsKidney Tubules, CollectingPotassium, DietarySodium, DietaryPotassium, DietarySodium, Dietary

Identifiers

PMID24051382
PMCPMC3786722
OpenAlexW1996371277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.