Trial reportAmerican journal of preventive medicine2013
C-reactive protein levels in African Americans: a diet and lifestyle randomized community trial.
Trial report in American journal of preventive medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01760902 (Diet & Activity Community Trial), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Diet & Activity Community Trial: High-Risk Inflammation
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Physical Activity Interventions With African American or Latino Men: A Systematic Review.American journal of men's health · 2018Pooled it
- The impact of a randomized dietary and physical activity intervention on chronic inflammation among obese African-American women.Women & health · 2020Trial
- Predictors of Retention among African Americans in a Randomized Controlled Trial to Test the Healthy Eating and Active Living in the Spirit (HEALS) Intervention.Ethnicity & disease · 2017Trial
- Perspective: Food Environment, Climate Change, Inflammation, Diet, and Health.Advances in nutrition (Bethesda, Md.) · 2025Review
- An Examination of Culturally Relevant Health Messages in African-American Churches.Journal of religion and health · 2023Article
- Ethnic disparities in mortality and group-specific risk factors in the UK Biobank.PLOS global public health · 2023Article
- Lower Life Satisfaction and Inflammation in African American Adults: Body Adiposity Mediation and Sex Moderation.Journal of personalized medicine · 2022Article
- The IMAGINE Intervention: Impacting Physical Activity, Body Fat, Body Mass Index, and Dietary Inflammatory Index.Translational journal of the American College of Sports Medicine · 2022Article
- Adherence to healthy lifestyle improved clinical outcomes in coronary artery disease patients after coronary intervention.Journal of the Chinese Medical Association : JCMA · 2021Article
- Antioxidant intake in relation to serum C-reactive protein in mid-life and older African Americans.Ethnicity & health · 2020Article
- Review
- Diet-related inflammation and risk of prostate cancer in the California Men's Health Study.Annals of epidemiology · 2019Article
- Sistas Inspiring Sistas Through Activity and Support (SISTAS): Study Design and Demographics of Participants.Ethnicity & disease · 2018Article
- Inflammatory potential of diet and risk of oral and pharyngeal cancer in a large case-control study from Italy.International journal of cancer · 2017Article
- Construct Validation of the Dietary Inflammatory Index among African Americans.The journal of nutrition, health & aging · 2017Article
- Longitudinal changes in the dietary inflammatory index: an assessment of the inflammatory potential of diet over time in postmenopausal women.European journal of clinical nutrition · 2016Observational
- Understanding the Association of Type 2 Diabetes Mellitus in Breast Cancer Among African American and European American Populations in South Carolina.Journal of racial and ethnic health disparities · 2016Article
- Disease Messaging in Churches: Implications for Health in African-American Communities.Journal of religion and health · 2016Article
- Association between inflammatory potential of diet and mortality in the Iowa Women's Health study.European journal of nutrition · 2016Article
- The Effect of Changes in Health Beliefs Among African-American and Rural White Church Congregants Enrolled in an Obesity Intervention: A Qualitative Evaluation.Journal of community health · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundChronic inflammation is linked to poor lifestyle behaviors and a variety of chronic diseases that are prevalent among African Americans, especially in the southeastern U.S. PURPOSE: The goal of the study was to test the effect of a community-based diet, physical activity, and stress reduction intervention conducted in 2009-2012 on reducing serum C-reactive protein (CRP) in overweight and obese African-American adults.
methodsAn RCT intervention was designed jointly by members of African-American churches and academic researchers. In late 2012, regression (i.e., mixed) models were fit that included both intention-to-treat and post hoc analyses conducted to identify important predictors of intervention success. Outcomes were assessed at 3 months and 1 year.
resultsAt baseline, the 159 individuals who were recruited in 13 churches and had evaluable outcome data were, on average, obese (BMI=33.1 [±7.1]) and had a mean CRP level of 3.7 (±3.9) mg/L. Reductions were observed in waist-to-hip ratio at 3 months (2%, p=0.03) and 1 year (5%, p<0.01). In female participants attending ≥60% of intervention classes, there was a significant decrease in CRP at 3 months of 0.8 mg/L (p=0.05), but no change after 1 year. No differences were noted in BMI or interleukin-6.
conclusionsIn overweight/obese, but otherwise "healthy," African-American church members with very high baseline CRP levels, this intervention produced significant reductions in CRP at 3 and 12 months, and in waist-to-hip ratio, which is an important anthropometric predictor of overall risk of inflammation and downstream health effects.
trial registrationThis study is registered at www.clinicaltrials.gov NCT01760902.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.