Evidence map›Paper›PMID 24050410›Full record

ArticleEmerging infectious diseases2013

Cryptococcus gattii infections in multiple states outside the US Pacific Northwest.

Julie R Harris, Shawn R Lockhart, Gail Sondermeyer, Duc J Vugia, Matthew B Crist, Melissa Tobin D'Angelo, Brenda Sellers, Carlos Franco-Paredes, Monear Makvandi, Chad Smelser and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 82 citations in OpenAlex.

  1. Article
  2. The Vacuolar Protein 8 (Vac8) Homolog inJournal of fungi (Basel, Switzerland) · 2025
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  3. Article
  4. Review
  5. Article
  6. Review
  7. A Fatal Fungal Infection:Open forum infectious diseases · 2022
    Article
  8. Ophthalmic manifestations ofInternational journal of ophthalmology · 2022
    Article
  9. MSG07: An International Cohort Study Comparing Epidemiology and Outcomes of Patients With Cryptococcus neoformans or Cryptococcus gattii Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  10. Cryptococcus gattii Meningitis in a Previously Healthy Young Woman: A Case Report.Clinical practice and cases in emergency medicine · 2021
    Article
  11. Review
  12. Article
  13. A case ofIDCases · 2021
    Article
  14. Review
  15. Article
  16. Medical mycology case reports · 2020
    Article
  17. Article
  18. False-Negative CSF Cryptococcal Antigen withCase reports in infectious diseases · 2020
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 2 countries.

Julie R Harris
Shawn R Lockhart
Gail Sondermeyer
Duc J Vugia
Matthew B Crist
Melissa Tobin D'Angelo
Brenda Sellers
Carlos Franco-Paredes
Monear Makvandi
Chad Smelser
John Greene
Danielle Stanek
Kimberly Signs
Randall J Nett
Tom Chiller
Benjamin J Park
Montana Department of Public Health and Human Services · USNew Mexico Department of Health · USCenters for Disease Control and Prevention · USGeorgia Department of Public Health · USMoffitt Cancer Center · USUC Irvine Health · USFlorida Department of Health · USHospital Infantil de México Federico Gómez · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clonal VGII subtypes (outbreak strains) of Cryptococcus gattii have caused an outbreak in the US Pacific Northwest since 2004. Outbreak-associated infections occur equally in male and female patients (median age 56 years) and usually cause pulmonary disease in persons with underlying medical conditions. Since 2009, a total of 25 C. gattii infections, 23 (92%) caused by non-outbreak strain C. gattii, have been reported from 8 non-Pacific Northwest states. Sixteen (64%) patients were previously healthy, and 21 (84%) were male; median age was 43 years (range 15-83 years). Ten patients who provided information reported no past-year travel to areas where C. gattii is known to be endemic. Nineteen (76%) patients had central nervous system infections; 6 (24%) died. C. gattii infection in persons without exposure to known disease-endemic areas suggests possible endemicity in the United States outside the outbreak-affected region; these infections appear to differ in clinical and demographic characteristics from outbreak-associated C. gattii. Clinicians outside the outbreak-affected areas should be aware of locally acquired C. gattii infection and its varied signs and symptoms.

Indexed as

AdolescentAdultAgedAged, 80 and overCryptococcosisCryptococcus gattiiDisease OutbreaksFemaleGenotypeHumansLung Diseases, FungalMaleMiddle AgedPhylogenyUnited StatesYoung AdultCryptococcusfungalfungigattiimeningitisPacific NorthwestpneumoniaUnited States

Identifiers

PMID24050410
PMCPMC3810751
OpenAlexW2155418642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.