Evidence map›Paper›PMID 24049693›Full record

ArticleBiomedical optics express2013

Multimodal in vivo imaging of oral cancer using fluorescence lifetime, photoacoustic and ultrasound techniques.

Hussain Fatakdawala, Shannon Poti, Feifei Zhou, Yang Sun, Julien Bec, Jing Liu, Diego R Yankelevich, Steven P Tinling, Regina F Gandour-Edwards, D Gregory Farwell and 1 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hussain FatakdawalaDepartment of Biomedical Engineering, University of California-Davis, Davis, CA 95616, USA.
Shannon Poti
Feifei Zhou
Yang Sun
Julien Bec
Jing Liu
Diego R Yankelevich
Steven P Tinling
Regina F Gandour-Edwards
D Gregory Farwell
Laura Marcu

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI PRIMO N. LARA · 2002 to 2026
$84.9M
Time-Resolved Spectroscopy of Unstable Arterial PlaquesR01HL067377 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MARCU, LAURA · 2001 to 2015
$5.2M
Engineering Approaches to Molecular Imaging TrainingT32EB003827 · NIBIB · UNIVERSITY OF CALIFORNIA DAVIS · PI FERRARA, KATHERINE W · 2004 to 2013
$1.6M
Multi-modal high-resolution technology for tissue diagnosticsR21RR025818 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MARCU, LAURA · 2009 to 2010
$584k
NCI NIH HHS P30 CA093373NCRR NIH HHS R21 RR025818NHLBI NIH HHS R01 HL067377NIBIB NIH HHS T32 EB003827
6 · The paper itself

Abstract

This work reports a multimodal system for label-free tissue diagnosis combining fluorescence lifetime imaging (FLIm), ultrasound backscatter microscopy (UBM), and photoacoustic imaging (PAI). This system provides complementary biochemical, structural and functional features allowing for enhanced in vivo detection of oral carcinoma. Results from a hamster oral carcinoma model (normal, precancer and carcinoma) are presented demonstrating the ability of FLIm to delineate biochemical composition at the tissue surface, UBM and related radiofrequency parameters to identify disruptions in the tissue microarchitecture and PAI to map optical absorption associated with specific tissue morphology and physiology.

Indexed as

(170.3880) Medical and biological imaging(170.5120) Photoacoustic imaging(170.7180) Ultrasound diagnostics(300.6500) Spectroscopy, time-resolved

Identifiers

PMID24049693
PMCPMC3771843

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.