Evidence map›Paper›PMID 24049689›Full record

ArticleBiomedical optics express2013

Dark-field circular depolarization optical coherence microscopy.

Kalpesh Mehta, Pengfei Zhang, Eugenia Li Ling Yeo, James Chen Yong Kah, Nanguang Chen

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kalpesh MehtaOptical Bioimaging Lab, Department of Bioengineering, National University of Singapore, 7 Engineering Drive 1, Blk E3A, 07-10, 117576 Singapore ; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, 28 Medical Drive, 117456 Singapore ; These authors contributed equally to this work.
Pengfei Zhang
Eugenia Li Ling Yeo
James Chen Yong Kah
Nanguang Chen
National University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optical coherence microscopy (OCM) is a widely used structural imaging modality. To extend its application in molecular imaging, gold nanorods are widely used as contrast agents for OCM. However, they very often offer limited sensitivity as a result of poor signal to background ratio. Here we experimentally demonstrate that a novel OCM implementation based on dark-field circular depolarization detection can efficiently detect circularly depolarized signal from gold nanorods and at the same time efficiently suppress the background signals. This results into a significant improvement in signal to background ratio.

Indexed as

(110.4500) Optical coherence tomography(120.5820) Scattering measurements(180.3170) Interference microscopy(290.5850) Scattering, particles(290.5855) Scattering, polarization

Identifiers

PMID24049689
PMCPMC3771839
OpenAlexW2035989110

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.