ReviewF1000prime reports2013
A mechanobiological perspective on cadherins and the actin-myosin cytoskeleton.
Review in F1000prime reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Malformin A1-mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy.FEBS open bio · 2026Article
- Piezo1 balances membrane and cortex tension to stabilize intercellular junctions and maintain the epithelial barrier.Journal of cell science · 2025Article
- Modulation of E-Cadherin Function through the AmotL2 Isoforms Promotes Ameboid Cell Invasion.Cells · 2023Article
- Homophilic and heterophilic cadherin bond rupture forces in homo- or hetero-cellular systems measured by AFM-based single-cell force spectroscopy.European biophysics journal : EBJ · 2021Article
- Actin-Based Adhesion Modules Mediate Cell Interactions with the Extracellular Matrix and Neighboring Cells.Cold Spring Harbor perspectives in biology · 2017Review
- Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity.Nature communications · 2017Article
- Loss of Gα12/13 exacerbates apical area dependence of actomyosin contractility.Molecular biology of the cell · 2016Article
- Mechanical phenotype of cancer cells: cell softening and loss of stiffness sensing.Oncotarget · 2015Article
- Control of cell-cell forces and collective cell dynamics by the intercellular adhesome.Nature cell biology · 2015Article
- Mechanotransduction of shear stress occurs through changes in VE-cadherin and PECAM-1 tension: implications for cell migration.Cell adhesion & migration · 2015Article
- Getting to the core of cadherin complex function in Caenorhabditis elegans.F1000Research · 2015Review
- Epithelial junctions and Rho family GTPases: the zonular signalosome.Small GTPases · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Classical cadherin receptors mediate morphogenetic cell-cell interactions within many tissues of the body. Their biological impact often entails cooperation between cadherin adhesion and the actin cytoskeleton, but how this may occur and - even more urgently - how this leads to morphogenetic outcomes are questions that remain poorly understood. Here, we suggest that the emerging field of cadherin mechanobiology provides a useful new perspective from which to revisit these issues. We propose that the actin cytoskeleton can be considered as an active agent that mediates how cadherin junctions resist, sense and transduce forces between cells.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.