Evidence map›Paper›PMID 24049614›Full record

ArticleInternational journal of preventive medicine2013

Suppressive impact of anethum graveolens consumption on biochemical risk factors of atherosclerosis in hypercholesterolemic rabbits.

Mahbubeh Setorki, Mahmoud Rafieian-Kopaei, Alireza Merikhi, Esfandiar Heidarian, Najmeh Shahinfard, Roya Ansari, Hamid Nasri, Nafiseh Esmael, Azar Baradaran

Open access · greenAbstract read
In one paragraph

Article in International journal of preventive medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Melissa officinalis L: A Review Study With an Antioxidant Prospective.Journal of evidence-based complementary & alternative medicine · 2017
    Review
  11. A review of plant-based compounds and medicinal plants effective on atherosclerosis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017
    Review
  12. Article
  13. Article
  14. Article
  15. The Role ofJournal of tropical medicine · 2016
    Review
  16. Antioxidant plants and diabetes mellitus.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015
    Review
  17. Review
  18. New concepts in nutraceuticals as alternative for pharmaceuticals.International journal of preventive medicine · 2014
    Review
  19. Atherosclerosis: process, indicators, risk factors and new hopes.International journal of preventive medicine · 2014
    Review
  20. Anethum graveolens and hyperlipidemia: A randomized clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Mahbubeh SetorkiDepartment of Biology, Izeh Branch, Islamic Azad University, Izeh, Iran.
Mahmoud Rafieian-Kopaei
Alireza Merikhi
Esfandiar Heidarian
Najmeh Shahinfard
Roya Ansari
Hamid Nasri
Nafiseh Esmael
Azar Baradaran
Isfahan University of Medical Sciences · IRShahrekord University of Medical Sciences · IRIzeh Islamic Azad University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to determine the effects of Anethum graveolens (Dill) powder on postprandial lipid profile, markers of oxidation and endothelial activation when added to a fatty meal.

methodsIn an experimental study, 32 rabbits were randomly designated into four diet groups: normal diet, high cholesterol diet (1%), high cholesterol diet plus 5% (w/w) dill powder and high cholesterol diet plus lovastatin (10 mg/kg, bw). The concentrations of glucose, total cholesterol (TC), low-density lipoproteins-cholesterol (LDL-C), alanine aminotransferase (alt), aspartate aminotransferase (ast), fibrinogen, factor VII, apolipoprotein B (ApoB), nitrite and nitrate were measured in blood samples following 15 h of fasting and 3 h after feeding.

resultsConcurrent use of A. graveolens powder or lovastatin significantly decreased ALT, TC, glucose, fibrinogen and LDL-C values in comparison with hypercholesterolemic diet group (P < 0.05). Consumption of A. graveolens or lovastatin did not change factor VII, ApoB, nitrite and nitrate levels significantly in comparison with hypercholesterolemic diet group. Intake of A. graveolens significantly decreased serum AST compared to hypercholesterolemic diet.

conclusionsA. graveolens might have some protective values against atherosclerosis and that it significantly affects some biochemical risk factors of this disease. Our findings also confirm the potential harmful effects of oxidized fats and the importance of dietary polyphenols in the meal.

Indexed as

Anethum graveolensatherosclerosishypercholesterolemiarabbits

Identifiers

PMID24049614
PMCPMC3775165
OpenAlexW1944734429

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.