ArticleArchives of medical science : AMS2013
Circulating vascular endothelial growth factor concentrations in patients with postmenopausal osteoporosis.
Article in Archives of medical science : AMS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
- Unravelling Osteoporosis: Key Genes and Potential Therapies.Journal of cellular and molecular medicine · 2025Article
- Associations Between Inflammatory and Bone Turnover Markers and Mortality in Hemodialysis Patients.Biomedicines · 2025Article
- Fluorinated Porcine Bone-Derived Hydroxyapatite Promotes Vascularized Osteogenesis by Coordinating Human Bone Marrow Mesenchymal Stem Cell/Human Umbilical Vein Endothelial Cell Complexes.Bioengineering (Basel, Switzerland) · 2024Article
- Diagnostic value of circulating bone turnover markers osteocalcin, cathepsin K, and osteoprotegerin for osteoporosis in middle-aged and elderly postmenopausal women.Archives of medical science : AMS · 2024Article
- Bone Remodeling in Mandible of Wistar Rats with Diabetes Mellitus and Osteoporosis.European journal of dentistry · 2023Article
- Construction of Bone Hypoxic Microenvironment Based on Bone-on-a-Chip Platforms.International journal of molecular sciences · 2023Review
- Multiscale molecular profiling of pathological bone resolves sexually dimorphic control of extracellular matrix composition.Disease models & mechanisms · 2021Article
- Early Changes of VEGF Levels After Zoledronic Acid in Women With Postmenopausal Osteoporosis: A Potential Role of Vitamin D.Frontiers in medicine · 2021Article
- Regulation of the Bone Vascular Network is Sexually Dimorphic.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019Article
- Vitreous concentrations of vascular endothelial growth factor as a potential biomarker for postoperative complications following pars plana vitrectomy.Archives of medical science : AMS · 2019Article
- Hypoxia Signaling in the Skeleton: Implications for Bone Health.Current osteoporosis reports · 2019Review
- The associations between the changes in serum inflammatory markers and bone mineral accrual in boys with overweight and obesity during pubertal maturation: a 3-year longitudinal study in Estonian boys.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Article
- Synergistic protection of bone vasculature and bone mass by desferrioxamine in osteoporotic mice.Molecular medicine reports · 2017Article
- Simultaneous visualisation of calcified bone microstructure and intracortical vasculature using synchrotron X-ray phase contrast-enhanced tomography.Scientific reports · 2017Article
- Impact of beverage consumption, age, and site dependency on dual energy X-ray absorptiometry (DEXA) measurements in perimenopausal women: a prospective study.Archives of medical science : AMS · 2017Article
- The effect of parathyroid hormone (1-84) treatment on serum bone morphogenetic protein 4 and vascular endothelial growth factor in postmenopausal women with established osteoporosis.Journal of endocrinological investigation · 2017Article
- Bone fracture healing in mechanobiological modeling: A review of principles and methods.Bone reports · 2017Review
- Treatment of denture-related stomatitis improves endothelial function assessed by flow-mediated vascular dilation.Archives of medical science : AMS · 2017Article
- Relationship between osteogenesis and angiogenesis in ovariectomized osteoporotic rats after exercise training.International journal of clinical and experimental pathology · 2017Article
- Correlation research between osteoporosis and left ventricular hypertrophy in older men.Archives of medical science : AMS · 2016Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe role of vascular endothelial growth factor (VEGF) in osteoporosis has not yet been clearly established. Vascular endothelial growth factor is an important part of bone formation. In the literature, although the effects of VEGF on bone metabolism were investigated by different studies, there are very rare studies analysing the association between osteoporosis and VEGF. In the present study, our objective was to investigate serum VEGF concentrations in patients with postmenopausal osteoporosis (PMO) and the correlation of serum VEGF levels and bone mineral density (BMD). MATERIAL AND
methodsThis study was performed on 35 PMO patients, and 30 age-matched healthy controls. Serum VEGF concentrations were measured using a quantitative sandwich enzyme immunoassay technique according to the manufacturer's instructions. Bone mineral density values were determined by dual energy X-ray absorptiometry (DEXA).
resultsSerum VEGF concentrations were statistically significantly lower in PMO patients than in controls (150 ±65 pg/ml, 260 ±135 pg/ml respectively; p = 0.005). A positive correlation was found between serum VEGF concentrations and BMD values (r = 0.63, p = 0.001).
conclusionsVascular endothelial growth factor concentrations were decreased in PMO patients and VEGF may play an important role in bone health.
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