ReviewJournal of Indian Society of Periodontology2013
Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease.
Review in Journal of Indian Society of Periodontology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Epidemiologic relationship between periodontitis and type 2 diabetes mellitus.BMC oral health · 2020Pooled it
- Inflammatory Status and Glycemic Control Level of Patients with Type 2 Diabetes and Periodontitis: A Randomized Clinical Trial.International journal of environmental research and public health · 2021Trial
- Trial
- Screening for Periodontitis Using Blood Biomarkers and Demographic Data: A Machine Learning Study.Oral health & preventive dentistry · 2026Article
- Integration of Endodontic Services Into Preventive Oral Health Care: A Narrative Review.International journal of dentistry · 2026Review
- Current Landscape of the Interrelationship Between Periodontitis, Type 2 Diabetes Mellitus, and COVID-19.International journal of molecular sciences · 2025Review
- Relationship between periodontitis, type 2 diabetes mellitus and COVID-19 disease: a narrative review.Frontiers in cellular and infection microbiology · 2025Review
- "The effects of non-surgical periodontal treatment plus zinc and magnesium supplementation on oxidative stress and antioxidants enzymes in type 2 diabetes patients: a quasi-experimental study".BMC oral health · 2024Article
- A semiparametric joint model for cluster size and subunit-specific interval-censored outcomes.Biometrics · 2023Article
- Association between Oral Hygiene and Metabolic Syndrome: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2021Review
- Porphyromonas gingivalis exacerbates the progression of fatty liver disease via CD36-PPARγ pathway.BMB reports · 2021Article
- Insight into the roles of melatonin in bone tissue and bone‑related diseases (Review).International journal of molecular medicine · 2021Review
- Role of Artesunate on cardiovascular complications in rats with type 1 diabetes mellitus.BMC endocrine disorders · 2021Article
- Effect of non-surgical periodontal treatment on three salivary adipokines in diabetic patients with periodontitis.Journal of dental research, dental clinics, dental prospects · 2020Article
- The Impacts of Synbiotic Supplementation on Periodontal Indices and Biomarkers of Oxidative Stress in Type 2 Diabetes Mellitus Patients with Chronic Periodontitis Under Non-Surgical Periodontal Therapy. A Double-Blind, Placebo-Controlled Trial.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Integration of oral health into primary health care: A systematic review.Journal of family medicine and primary care · 2019Review
- MMP-2 salivary activity in type 2 diabetes mellitus patients.Diabetology & metabolic syndrome · 2019Article
- Physical Exercise Improves Glycemic and Inflammatory Profile and Attenuates Progression of Periodontitis in Diabetic Rats (HFD/STZ).Nutrients · 2018Article
- Metformin ameliorates diabetic nephropathy in a rat model of low-dose streptozotocin-induced diabetes.Experimental and therapeutic medicine · 2017Article
- The Effect of Diabetes Mellitus Type I on Periodontal and Dental Status.Journal of clinical and diagnostic research : JCDR · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Both diabetes and periodontitis are chronic diseases. Diabetes has many adverse effects on the periodontium, and conversely periodontitis may have deleterious effects further aggravating the condition in diabetics. The potential common pathophysiologic pathways include those associated with inflammation, altered host responses, altered tissue homeostasis, and insulin resistance. This review examines the relationship that exists between periodontal diseases and diabetes mellitus with a focus on potential common pathophysiologic mechanisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.