Evidence map›Paper›PMID 24049168›Full record

ArticleJournal of virology2013

Epstein-Barr virus and human herpesvirus 6 detection in a non-Hodgkin's diffuse large B-cell lymphoma cohort by using RNA sequencing.

Michael J Strong, Tina O'Grady, Zhen Lin, Guorong Xu, Melody Baddoo, Chris Parsons, Kun Zhang, Christopher M Taylor, Erik K Flemington

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. RNA Sequencing of theJournal of virology · 2019
    Article
  15. Review
  16. Article
  17. Lymphoproliferative Syndromes Associated with Human Herpesvirus-6A and Human Herpesvirus-6B.Mediterranean journal of hematology and infectious diseases · 2018
    Review
  18. Tumour virology in the era of high-throughput genomics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Michael J StrongDepartment of Pathology, Tulane University, New Orleans, Louisiana, USA.
Tina O'Grady
Zhen Lin
Guorong Xu
Melody Baddoo
Chris Parsons
Kun Zhang
Christopher M Taylor
Erik K Flemington
Tulane University · USLouisiana Cancer Research Center · USChildren's Hospital of New Orleans · USLouisiana State University Health Sciences Center New Orleans · USXavier University of Louisiana · US

Funding

Mentoring a Cancer Genetics ProgramP20GM103518 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI DEININGER, PRESCOTT L. · 2012 to 2013
$4.3M
Intercellular communication in Epstein Barr virus reactivationR01AI101046 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI FLEMINGTON, ERIK K · 2012 to 2016
$1.9M
Role of the cellular microRNA, miR-155, in EBV type III latency signalingR01CA138268 · NCI · TULANE UNIVERSITY OF LOUISIANA · PI FLEMINGTON, ERIK K · 2009 to 2013
$1.5M
Regulation of Epstein Barr virus reactivation through the co-activators, CBP/p300R01CA124311 · NCI · TULANE UNIVERSITY OF LOUISIANA · PI FLEMINGTON, ERIK K · 2007 to 2011
$1.3M
Human cytomegalovirus in the promotion of glioblastoma multiforme pathogenesisF30CA177267 · NCI · TULANE UNIVERSITY OF LOUISIANA · PI STRONG, MICHAEL JAMES · 2013 to 2016
$129k
NCI NIH HHS F30 CA177267NCI NIH HHS F30CA177267NCI NIH HHS R01 CA124311NCI NIH HHS R01CA124311NCI NIH HHS R01 CA138268NCI NIH HHS R01CA138268NIAID NIH HHS R01 AI101046NIGMS NIH HHS P20 GM103518NIGMS NIH HHS P20GM103518
6 · The paper itself

Abstract

Comprehensive virome analysis of RNA sequence (RNA-seq) data sets from 118 non-Hodgkin's B-cell lymphomas revealed a small subset that is positive for Epstein-Barr virus (EBV) or human herpesvirus 6B (HHV-6B), with one coinfection. EBV transcriptome analysis revealed expression of the latency genes RPMS1, LMP1, and LMP2, with one sample additionally showing a high level of early lytic expression and another sample showing a high level of EBNA2 expression. HHV-6B transcriptome analysis revealed that the majority of genes were transcribed.

Indexed as

Cohort StudiesEpstein-Barr Virus InfectionsGene Expression Regulation, ViralHerpesvirus 4, HumanHerpesvirus 6, HumanHumansLymphoma, Large B-Cell, DiffuseRoseolovirus InfectionsSequence Analysis, RNAViral ProteinsViral Proteins

Identifiers

PMID24049168
PMCPMC3838131
OpenAlexW2135334986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.