Evidence map›Paper›PMID 24049164›Full record

ArticleJournal of virology2013

A simplified positive-sense-RNA virus construction approach that enhances analysis throughput.

Bunpote Siridechadilok, Methee Gomutsukhavadee, Thunyarat Sawaengpol, Sutha Sangiambut, Chunya Puttikhunt, Kwanrutai Chin-inmanu, Prapat Suriyaphol, Prida Malasit, Gavin Screaton, Juthathip Mongkolsapaya

Open access · hybridAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Bunpote SiridechadilokNational Center For Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency, Pathumthani, Thailand.
Methee Gomutsukhavadee
Thunyarat Sawaengpol
Sutha Sangiambut
Chunya Puttikhunt
Kwanrutai Chin-inmanu
Prapat Suriyaphol
Prida Malasit
Gavin Screaton
Juthathip Mongkolsapaya
National Center for Genetic Engineering and Biotechnology · THNational Science and Technology Development Agency · THHammersmith Hospital · GBImperial College London · GBMahidol University · THSiriraj Hospital · TH

Funding

Medical Research Council G0400720Medical Research Council G0801508Wellcome Trust 095541
6 · The paper itself

Abstract

Here we present an approach that advances the throughput of a genetic analysis of a positive-sense RNA virus by simplifying virus construction. It enabled comprehensive dissection of a complex, multigene phenotype through rapid derivation of a large number of chimeric viruses and construction of a mutant library directly from a virus pool. The versatility of the approach described here expands the applicability of diverse genetic approaches to study these viruses.

Indexed as

Gene LibraryGenetic EngineeringRNA, ViralRNA VirusesRNA, Viral

Identifiers

PMID24049164
PMCPMC3838137
OpenAlexW2048727774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.