ReviewQJM : monthly journal of the Association of Physicians2014
Predictive genetic testing for complex diseases: a public health perspective.
Review in QJM : monthly journal of the Association of Physicians, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- How is genetic testing evaluated? A systematic review of the literature.European journal of human genetics : EJHG · 2018Pooled it
- The Diagnostic Yield and Implications of Targeted Founder Pathogenic Variant Testing in an Israeli Cohort.Cancers · 2023Article
- Precision medicine from a citizen perspective: a survey of public attitudes towards pharmacogenomics in Flanders.BMC medical genomics · 2022Article
- Replication of gene polymorphisms associated with periodontitis-related traits in an elderly cohort: the Washington Heights/Inwood Community Aging Project Ancillary Study of Oral Health.Journal of clinical periodontology · 2022Article
- Clinical validation of genomic functional screen data: Analysis of observedHGG advances · 2022Article
- Donor genetic backgrounds contribute to the functional heterogeneity of stem cells and clinical outcomes.Stem cells translational medicine · 2020Article
- I Would Never Take Preventive Medication! Perspectives and Information Needs of People Who Underwent Predictive Tests for Rheumatoid Arthritis.Arthritis care & research · 2020Article
- Genomics knowledge and attitudes among European public health professionals: Results of a cross-sectional survey.PloS one · 2020Article
- Attitudes toward the right to autonomous decision-making in psychiatric genetic testing: Controversial and context-dependent.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2019Article
- Article
- Population-Wide Genetic Risk Prediction of Complex Diseases: A Pilot Feasibility Study in Macau Population for Precision Public Healthcare Planning.Scientific reports · 2018Article
- Needles, Haystacks and Next-Generation Genetic Sequencing.Health matrix (Cleveland, Ohio : 1991) · 2018Article
- The Evolution of Public Health Genomics: Exploring Its Past, Present, and Future.Frontiers in public health · 2018Review
- Pragmatic medicine in solid cancer: a translational alternative to precision medicine.OncoTargets and therapy · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
From a public health perspective, systematic, evidence-based technology assessments and economic evaluations are needed to guide the incorporation of genomics into clinical and public health practice. However, scientific evidence on the effectiveness of predictive genetic tests is difficult to obtain. This review first highlights the similarities and differences between traditional screening tests and predictive genetic testing for complex diseases and goes on to describe frameworks for the evaluation of genetic testing that have been developed in recent years providing some evidence that currently genetic tests are not used in an appropriate way. Nevertheless, evidence-based recommendations are already available for some genomic applications that can reduce morbidity and mortality and many more are expected to emerge over the next decade. The time is now ripe for the introduction of a range of genetic tests into healthcare practice, but this will require the development of specific health policies, proper public health evaluations, organizational changes within the healthcare systems, capacity building among the healthcare workforce and the education of the public.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.