ArticleInternal and emergency medicine2014
Delirium is a predictor of in-hospital mortality in elderly patients with community acquired pneumonia.
Article in Internal and emergency medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Mortality Risk Following Delirium in Older Inpatients: A Systematic Review and Meta-Analysis.Worldviews on evidence-based nursing · 2025Pooled it
- A call to action for delirium research: Meta-analysis and regression of delirium associated mortality.BMC geriatrics · 2020Pooled it
- Neurofilament light chain levels predict encephalopathy and outcome in community-acquired pneumonia.Annals of clinical and translational neurology · 2023Observational
- Pneumonia, Aspiration Pneumonia, or Frailty-Associated Pneumonia?Geriatrics (Basel, Switzerland) · 2022Article
- Intensive care unit management of uncomplicated type B aortic dissection in relation to treatment period: a retrospective observational study.Journal of Yeungnam medical science · 2022Article
- Risk factors for delirium among SARS-CoV-2 positive veterans.Psychiatry research · 2022Article
- Intracerebral Infection withJournal of Alzheimer's disease reports · 2022Article
- Development and validation of a new scoring system for prognostic prediction of community-acquired pneumonia in older adults.Scientific reports · 2021Article
- Fostering healthy aging: The interdependency of infections, immunity and frailty.Ageing research reviews · 2021Review
- COVID-19 in adults with dementia: clinical features and risk factors of mortality-a clinical cohort study on 125 patients.Alzheimer's research & therapy · 2021Article
- [Pneumonia in old age].Der Pneumologe · 2021Review
- Treatment of Delirium in Older Persons: What We Should Not Do!International journal of molecular sciences · 2020Review
- Delirium: A Frequent Manifestation in COVID-19 Older Patients.Clinical interventions in aging · 2020Article
- Characteristics and Management of Community-Acquired Pneumonia in the Era of Global Aging.Medical sciences (Basel, Switzerland) · 2018Review
- Early identification of severe community-onset pneumonia in "frail elderly patient".Internal and emergency medicine · 2014Article
- Factors Related to the Severity of Delirium in the Elderly Patients With Infection.Gerontology & geriatric medicineArticle
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7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Community acquired pneumonia (CAP) is a common reason for hospitalization and death in elderly people. Many predictors of in-hospital outcome have been studied in the general population with CAP. However, data are lacking on the prognostic significance of conditions unique to older patients, such as delirium and the coexistence of multiple comorbidities. The aim of this study was to evaluate predictors of in-hospital outcome in elderly patients hospitalized for CAP. In this retrospective study, consecutive patients with CAP aged ≥65 years were enrolled between January 2011 and June 2012 in two general wards. Clinical and laboratory characteristics were collected from electronic medical records. The end-point of the study was the occurrence of in-hospital death. 443 patients (mean age 81.8 ± 7.5, range 65-99 years) were enrolled. More than 3 comorbidities were present in 31 % of patients. Mean confusion, blood urea nitrogen, respiratory rate, blood pressure and age ≥65 years (CURB-65) score was 2.5 ± 0.7 points. Mean length of stay was 7.6 ± 5.7 days. In-hospital death occurred in 54 patients (12.2 %). At multivariate analysis, independent predictors of in-hospital death were: chronic obstructive pulmonary disease (COPD) (OR 6.21, p = 0.005), occurrence of at least one episode of delirium (OR 5.69, p = 0.017), male sex (OR 5.10, p < 0.0001), and CURB-65 score (OR 3.98, p < 0.0001). Several predictors of in-hospital death (COPD, male gender, CURB-65) in patients with CAP older than 65 years are similar to those of younger patients. In this cohort of elderly patients, the occurrence of delirium was highly prevalent and represented a distinctive predictor of death.
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