ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2013
Sound localization ability and glycinergic innervation of the superior olivary complex persist after genetic deletion of the medial nucleus of the trapezoid body.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Computational Model for Synthesizing Auditory Brainstem Responses to Assess Neuronal Alterations in Aging and Autistic Animal Models.Journal of the Association for Research in Otolaryngology : JARO · 2026Article
- Cochlear nucleus spatial transcriptomes of normal and hearing loss mice reveal a critical role of Spp1 in bushy cells.Cell research · 2026Article
- Neurexins control the strength and precise timing of glycinergic inhibition in the auditory brainstem.eLife · 2024Article
- Bidirectional remodeling of the central auditory system caused by unilateral auditory deprivation.Frontiers in neurology · 2024Review
- Obliteration of a glycinergic projection to the medial geniculate in an animal model of autism.Frontiers in cellular neuroscience · 2024Article
- Article
- Age-Related Hearing Loss: Sensory and Neural Etiology and Their Interdependence.Frontiers in aging neuroscience · 2022Review
- The Untouchable Ventral Nucleus of the Trapezoid Body: Preservation of a Nucleus in an Animal Model of Autism Spectrum Disorder.Frontiers in integrative neuroscience · 2021Article
- The Calyx of Held: A Hypothesis on the Need for Reliable Timing in an Intensity-Difference Encoder.Neuron · 2018Review
- Glial Cell Expansion Coincides with Neural Circuit Formation in the Developing Auditory Brainstem.Developmental neurobiology · 2018Article
- Specific synaptic input strengths determine the computational properties of excitation-inhibition integration in a sound localization circuit.The Journal of physiology · 2018Article
- Ultrastructural basis of strong unitary inhibition in a binaural neuron.The Journal of physiology · 2018Article
- Spatial hearing ability of the pigmented Guinea pig (Cavia porcellus): Minimum audible angle and spatial release from masking in azimuth.Hearing research · 2018Article
- Absence of Claudin 11 in CNS Myelin Perturbs Behavior and Neurotransmitter Levels in Mice.Scientific reports · 2018Article
- Neurotransmitters and Receptors Changes in Medial Nucleus of the Trapezoid Body (MNTB) of Early-Developmental Rats with Single-Side Deafness.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Knockout Mice for Dyslexia Susceptibility Gene Homologs KIAA0319 and KIAA0319L have Unaffected Neuronal Migration but Display Abnormal Auditory Processing.Cerebral cortex (New York, N.Y. : 1991) · 2017Article
- Acoustic startle modification as a tool for evaluating auditory function of the mouse: Progress, pitfalls, and potential.Neuroscience and biobehavioral reviews · 2017Review
- Cellular and Molecular Underpinnings of Neuronal Assembly in the Central Auditory System during Mouse Development.Frontiers in neural circuits · 2017Review
- En1 is necessary for survival of neurons in the ventral nuclei of the lateral lemniscus.Developmental neurobiology · 2016Article
- Aging effects on the binaural interaction component of the auditory brainstem response in the Mongolian gerbil: Effects of interaural time and level differences.Hearing research · 2016Article
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7 authors.
Funding
Abstract
The medial nucleus of the trapezoid body (MNTB) in the superior olivary complex (SOC) is an inhibitory hub considered critical for binaural sound localization. We show that genetic ablation of MNTB neurons in mice only subtly affects this ability by prolonging the minimum time required to detect shifts in sound location. Furthermore, glycinergic innervation of the SOC is maintained without an MNTB, consistent with the existence of parallel inhibitory inputs. These findings redefine the role of MNTB in sound localization and suggest that the inhibitory network is more complex than previously thought.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.