ArticleG3 (Bethesda, Md.)2013
Allelic variation in a cellulose synthase gene (PtoCesA4) associated with growth and wood properties in Populus tomentosa.
Article in G3 (Bethesda, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 32 citations in OpenAlex.
- The PtoERF1-PtomiR393a-PtoFBL4 module confers drought tolerance via ABA-auxin crosstalk in Populus.The New phytologist · 2026Article
- Identification of miR171a-International journal of molecular sciences · 2025Article
- Genetic Diversity and Association Analysis of Traits Related to Water-Use Efficiency and Nitrogen-Use Efficiency ofInternational journal of molecular sciences · 2024Article
- Allelic variations of WAK106-E2Fa-DPb1-UGT74E2 module regulate fibre properties in Populus tomentosa.Plant biotechnology journal · 2024Article
- Tissue-Specific Transcriptomes in the Secondary Cell Wall Provide an Understanding of Stem Growth Enhancement inBiology · 2023Article
- Development of EST-SSR markers and association mapping with floral traits in Syringa oblata.BMC plant biology · 2020Article
- Genetic interactions among Pto-miR319 family members and their targets influence growth and wood properties in Populus tomentosa.Molecular genetics and genomics : MGG · 2020Article
- Prime Editing Technology and Its Prospects for Future Applications in Plant Biology Research.Biodesign research · 2020Review
- Indole-3-acetic acid has long-term effects on long non-coding RNA gene methylation and growth in Populus tomentosa.Molecular genetics and genomics : MGG · 2019Article
- Single-nucleotide polymorphisms(SNPs) in a sucrose synthase gene are associated with wood properties in Catalpa fargesii bur.BMC genetics · 2018Article
- Identification and allelic dissection uncover roles of lncRNAs in secondary growth of Populus tomentosa.DNA research : an international journal for rapid publication of reports on genes and genomes · 2017Article
- Association mapping for floral traits in cultivated Paeonia rockii based on SSR markers.Molecular genetics and genomics : MGG · 2017Article
- Allelic variation in PtoPsbW associated with photosynthesis, growth, and wood properties in Populus tomentosa.Molecular genetics and genomics : MGG · 2017Article
- Allelic Interactions amongFrontiers in plant science · 2017Article
- Association genetics in Populus reveals the interactions between Pto-miR160a and its target Pto-ARF16.Molecular genetics and genomics : MGG · 2016Article
- Association mapping in Populus reveals the interaction between Pto-miR530a and its target Pto-KNAT1.Planta · 2015Article
- Association genetics in Populus reveals the interactions between Pt-miR397a and its target genes.Scientific reports · 2015Article
- Identification of additive, dominant, and epistatic variation conferred by key genes in cellulose biosynthesis pathway in Populus tomentosa†.DNA research : an international journal for rapid publication of reports on genes and genomes · 2015Article
- Transcriptomic analysis reveals importance of ROS and phytohormones in response to short-term salinity stress in Populus tomentosa.Frontiers in plant science · 2015Article
- Association of allelic variation in PtoXET16A with growth and wood properties in Populus tomentosa.International journal of molecular sciences · 2014Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lignocellulosic biomass from trees provides a renewable feedstock for biofuels, lumber, pulp, paper, and other uses. Dissecting the mechanism underlying natural variation of the complex traits controlling growth and lignocellulose biosynthesis in trees can enable marker-assisted breeding to improve wood quality and yield. Here, we combined linkage disequilibrium (LD)-based association analysis with traditional linkage analysis to detect the genetic effect of a Populus tomentosa cellulose synthase gene, PtoCesA4. PtoCesA4 is strongly expressed in developing xylem and leaves. Nucleotide diversity and LD in PtoCesA4, sampled from the P. tomentosa natural distribution, revealed that PtoCesA4 harbors high single nucleotide polymorphism (SNP) diversity (πT = 0.0080 and θw = 0.0098) and low LD (r(2) ≥ 0.1, within 1400 bp), demonstrating that the potential of a candidate-gene-based LD approach in understanding the molecular basis underlying quantitative variation in this species. By combining single SNP, multi-SNP, and haplotype-based associations in an association population of 460 individuals with single SNP linkage analysis in a family-based linkage populations (1200 individuals), we identified three strong associations (false discovery rate Q < 0.05) in both populations. These include two nonsynonymous markers (SNP49 associated with α-cellulose content and SNP59 associated with fiber width) and a noncoding marker (SNP18 associated with α-cellulose content). Variation in RNA transcript abundance among genotypic classes of SNP49 was confirmed in these two populations. Therefore, combining different methods allowed us to examine functional PtoCesA4 allelic variation underlying natural variation in complex quantitative traits related to growth and lignocellulosic biosynthesis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.