Evidence map›Paper›PMID 24048581›Full record

Trial reportWorld journal of surgery2013

Goal-directed fluid therapy in gastrointestinal surgery in older coronary heart disease patients: randomized trial.

Hong Zheng, Hai Guo, Jian-Rong Ye, Lin Chen, Hai-Ping Ma

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02559141 (Non-invasive Early Goal Directed Therapy in Colorectal Surgery), which is not on this map. Cited by 31 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 13 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02559141 nacompletednot on this mapstarted 2014, after this paper: background citation

Non-invasive Early Goal Directed Therapy in Colorectal Surgery: a Feasibility Study

TypeinterventionalSponsorUniversity Hospital Schleswig-HolsteinRan2014 to 2015Enrolled80ConditionsPerioperative/Postoperative Complications, C.Surgical Procedure, Digestive SystemArmsDobutamine
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 13 syntheses or guidelines pooled it, 61 citations in OpenAlex.

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  18. Article
  19. Goal-directed therapy: what is the goal again?Perioperative medicine (London, England) · 2025
    Review
  20. The Effect of Goal-directed Fluid Management based on Stroke Volume Variation on ICU Length of Stay in Elderly Patients Undergoing Elective Craniotomy: A Randomized Controlled Trial.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hong ZhengDepartment of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical University, No. 137, Li yu Shan Street, Urumqi, 830054, Xinjiang, China, xjzhenghong@aliyun.com.
Hai Guo
Jian-Rong Ye
Lin Chen
Hai-Ping Ma
Xinjiang Medical University · CNFirst Affiliated Hospital of Xinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur aim was to determine whether substitution of goal-directed fluid therapy (GDT) (perioperative fluid administration) for traditional therapy to manage elderly patients with coronary heart disease scheduled for gastrointestinal (GI) surgery was advantageous. We determined if it would reduce cardiac complications and shorten time to recovery and discharge.

methodsAltogether, 60 of these elderly patients were randomized into GDT (n = 30) and control (n = 30) groups. In the GDT group, fluid management was carried out under guidance of hemodynamic status indicators. Types and quantities of fluids administered, blood loss, intraoperative urine output, time of extubation, intensive care unit (ICU) stay, hospital stay, postoperative adverse cardiac events, and GI complications were recorded.

resultsTotal fluids infused were 2,910 ± 645 ml (GDT group) and 3,640 ± 771 ml (control group) (p < 0.05). Numbers of adverse cardiac events in the two groups were not significantly different (p = 0.121). Return of GI function was significantly faster in the GDT group (p < 0.001). Median ICU stay was 32.5 h in the GDT group and 47.5 h in the control group (p < 0.001). Median hospital stay was 18 days in the GDT group and 22 days in the control group (p < 0.001).

conclusionsGDT was associated with shorter ICU stay and time to discharge and faster return of GI function compared to traditional fluid therapy. The number of adverse cardiac events was similar in the two groups.

Indexed as

Elective Surgical ProceduresAgedAged, 80 and overCoronary DiseaseFemaleFluid TherapyGastrointestinal DiseasesHumansLength of StayMalePerioperative CarePostoperative ComplicationsRecovery of FunctionSingle-Blind MethodTreatment Outcome

Identifiers

PMID24048581
OpenAlexW2029898247

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.