ArticleAmerican journal of hypertension2014
Obesity and overweight associated with increased carotid diameter and decreased arterial function in young otherwise healthy men.
Article in American journal of hypertension, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 49 citations in OpenAlex.
- Carotid Intima-Media Thickness in Young Healthy Adults in Saudi Arabia: A Pilot Study of Preliminary CIMT Measurements and Cardiovascular Risk Assessment Using a Handheld Ultrasound Device.Healthcare (Basel, Switzerland) · 2026Article
- The Effects of Previous Amenorrhea on Endothelial and Vascular Function.International journal of endocrinology · 2025Article
- Evaluation of subclinical atherosclerosis in obese patients with three noninvasive methods: Arterial stiffness, carotid intima-media thickness, and biomarkers of endothelial dysfunction.Archives of endocrinology and metabolism · 2023Article
- Article
- Arterial stiffness nomogram identification by cluster analysis: A new approach of vascular phenotype modeling.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- The effects of high-intensity interval training and moderate-intensity continuous training on visceral fat and carotid hemodynamics parameters in obese adults.Journal of exercise science and fitness · 2022Article
- Arterial Stiffness Determinants for Primary Cardiovascular Prevention among Healthy Participants.Journal of clinical medicine · 2022Article
- Pulse pressure and the risk of renal hyperfiltration in young adults: Results from Korea National Health and Nutrition Examination Survey (2010-2019).Frontiers in medicine · 2022Article
- Low Fitness and High Fatness: The "Double Whammy" on Vascular Health.Taehan Sup'och'u Uihakhoe chi = The Korean journal of sports medicine · 2021Article
- Independent and Synergistic Effects of High Blood Pressure and Obesity on Retinal Vasculature in Young Children: The Hong Kong Children Eye Study.Journal of the American Heart Association · 2021Article
- Article
- Relationship between body mass index and arterial stiffness in a health assessment Chinese population.Medicine · 2020Article
- Arterial Stiffness and Endothelial Function in Young Obese Patients - Vascular Resistance Matters.Journal of atherosclerosis and thrombosis · 2019Article
- Vascular Dysfunction among Malaysian Men with Increased BMI: An Indication of Synergistic Effect of Free Testosterone and Inflammation.Medicina (Kaunas, Lithuania) · 2019Article
- Pulse wave velocity is decreased with obesity in an elderly Chinese population.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Article
- Greater Height Is Associated with a Larger Carotid Lumen Diameter.Medicines (Basel, Switzerland) · 2019Article
- The pro-atherogenic response to disturbed blood flow is increased by a western diet, but not by old age.Scientific reports · 2019Article
- Insulin resistance is associated with subclinical vascular disease in humans.World journal of diabetes · 2019Review
- Higher blood pressure and lower cardiac vagal activity in obese young individuals in supine and seated position.Journal of clinical and translational research · 2018Article
Corrections and comments
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Authors and funding
9 authors at 7 institutions in 2 countries.
Funding
Abstract
backgroundObesity is linked to cardiovascular disease, stroke, increased mortality and vascular remodeling. Although increased arterial diameter is associated with multiple cardiovascular risk factors and obesity, it is unknown whether lumen enlargement is accompanied by unfavorable vascular changes in young and otherwise healthy obese individuals. The purpose of this study was to compare carotid and brachial artery diameter, blood pressure, arterial stiffness, and endothelial function in young, apparently healthy, normal-weight, overweight, and obese male subjects.
methodsOne hundred sixty-five male subjects (27.39±0.59 years) were divided into 3 groups (normal weight, overweight, and obese) according to body mass index. Subjects underwent cardiovascular measurements to determine arterial diameter, function, and stiffness.
resultsAfter adjusting for age, the obese group had significantly greater brachial, carotid, and aortic pressures, brachial pulse wave velocity, carotid intima media thickness, and carotid arterial diameter compared with both the overweight and normal-weight groups.
conclusionsObesity is associated with a much worse arterial profile, as an increased carotid lumen size was accompanied by higher blood pressure, greater arterial stiffness, and greater carotid intima media thickness in obese compared with overweight or normal-weight individuals. These data suggest that although obesity may be a factor in arterial remodeling, such remodeling is also accompanied by other hemodynamic and arterial changes consistent with reduced arterial function and increased cardiovascular risk.
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