ArticleThe American journal of clinical nutrition2013
Heritability of objectively assessed daily physical activity and sedentary behavior.
Article in The American journal of clinical nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
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Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prenatal, birth and early life predictors of sedentary behavior in young people: a systematic review.The international journal of behavioral nutrition and physical activity · 2016Pooled it
- A systematic review of correlates of sedentary behaviour in adults aged 18-65 years: a socio-ecological approach.BMC public health · 2016Pooled it
- The Determinants of the Preferred Walking Speed in Individuals with Obesity.Obesity facts · 2019Trial
- Association between ADHD symptoms and device-measured physical activity and sedentary behavior in childhood: A population-based twin study.JCPP advances · 2026Article
- Evidence for overlapping genetic architecture between lifestyle factors and severe mental disorders with different patterns across diagnoses.EBioMedicine · 2026Article
- Genetic Determinants of Leisure-Time Physical Activity in the Taiwanese Population: A Genome-Wide Association Study.Medicine and science in sports and exercise · 2025Article
- Genetic liability to sedentary behaviour and cardiovascular disease incidence in the FinnGen and HUNT cohorts.British journal of sports medicine · 2025Article
- A Mendelian randomization study: physical activities and chronic kidney disease.Renal failure · 2024Article
- Longitudinal associations between fruit and vegetable intakes and depressive symptoms in middle-aged and older adults from four international twin cohorts.Scientific reports · 2024Article
- Genetic and environmental influence on resting state networks in young male and female adults: a cartographer mapping study.Human brain mapping · 2023Article
- Leisure sedentary behaviour increases the risk of venous thromboembolism: a Mendelian randomisation study.BMC cardiovascular disorders · 2023Article
- Selective breeding for physical inactivity produces cognitive deficitsFrontiers in aging neuroscience · 2023Article
- The genetic case for cardiorespiratory fitness as a clinical vital sign and the routine prescription of physical activity in healthcare.Genome medicine · 2021Article
- Associations Between Anxiety Symptoms and Health-Related Quality of Life: A Population-Based Twin Study in Sri Lanka.Behavior genetics · 2021Article
- Is the positive relationship of infant weight gain with adolescent adiposity attenuated by moderate-to-vigorous physical activity in childhood? Evidence from the Millennium Cohort Study.International journal of obesity (2005) · 2021Article
- Polygenic Risk Scores and Physical Activity.Medicine and science in sports and exercise · 2020Article
- Heritability of objectively assessed and self-reported sedentary behavior.Scandinavian journal of medicine & science in sports · 2020Article
- Impact of dopamine-related genetic variants on physical activity in old age - a cohort study.The international journal of behavioral nutrition and physical activity · 2020Article
- Genetic variants associated with exercise performance in both moderately trained and highly trained individuals.Molecular genetics and genomics : MGG · 2020Article
- Overexpression of Protein Kinase Inhibitor Alpha Reverses Rat Low Voluntary Running Behavior.Molecular neurobiology · 2019Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundTwin and family studies that estimated the heritability of daily physical activity have been limited by poor measurement quality and a small sample size.
objectiveWe examined the heritability of daily physical activity and sedentary behavior assessed objectively by using combined heart rate and movement sensing in a large twin study.
designPhysical activity traits were assessed in daily life for a mean (± SD) 6.7 ± 1.1 d in 1654 twins from 420 monozygotic and 352 dizygotic same-sex twin pairs aged 56.3 ± 10.4 y with body mass index (in kg/m(2)) of 26.1 ± 4.8. We estimated the average daily movement, physical activity energy expenditure, and time spent in moderate-to-vigorous intensity physical activity and sedentary behavior from heart rate and acceleration data. We used structural equation modeling to examine the contribution of additive genetic, shared environmental, and unique environmental factors to between-individual variation in traits.
resultsAdditive genetic factors (ie, heritability) explained 47% of the variance in physical activity energy expenditure (95% CI: 23%, 53%) and time spent in moderate-to-vigorous intensity physical activity (95% CI: 29%, 54%), 35% of the variance in acceleration of the trunk (95% CI: 0%, 44%), and 31% of the variance in the time spent in sedentary behavior (95% CI: 9%, 51%). The remaining variance was predominantly explained by unique environmental factors and random error, whereas shared environmental factors played only a marginal role for all traits with a range of 0-15%.
conclusionsThe between-individual variation in daily physical activity and sedentary behavior is mainly a result of environmental influences. Nevertheless, genetic factors explain up to one-half of the variance, suggesting that innate biological processes may be driving some of our daily physical activity.
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