Trial reportThe New England journal of medicine2013
Effects of bracing in adolescents with idiopathic scoliosis.
Trial report in The New England journal of medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 9 registered trials, which are not on this map. Cited by 531 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bracing in Adolescent Idiopathic Scoliosis Trial (BrAIST)
Investigation of the Effects of Spinal Stabilization and Body Awareness Exercises on Subjective Vertical Perception, Curve Magnitude, Body Symmetry and Quality of Life in Adolescent Idiopathic Scoliosis
Using Radiation-free Ultrasound for Screening Scoliosis Among School Children in Hong Kong to Reduce Unnecessary X-ray Exposure
Three-dimensional Effects of Bracing in Adolescent Idiopathic Scoliosis
End-growth Results of Tailored Treatment in 1938 Adolescents With High Risk Idiopathic Scoliosis: a Cohort Study From a Prospective Clinical Database
Dysport ® (abobotulinumtoxinA) as an Adjunctive Treatment to Bracing in the Management of Adolescent Idiopathic Scoliosis
Development and Short-Term Evaluation of a Novel Semi-Rigid Brace for Adolescent Idiopathic Scoliosis: Results From a Multicenter Prospective Observational Study of the First 60 Patients
Comparative Effectiveness of Physiotherapeutic Scoliosis-Specific Exercises Versus General Exercises in Adolescents With Idiopathic Scoliosis: A Randomized Controlled Trial
Evaluating the Impact of a Smartphone App on Health Outcomes and Treatment Adherence in Adolescents With Idiopathic Scoliosis: A Mixed Method Quasi-Experimental Study
Who cites it
531 citing papers in PubMed, 11 syntheses or guidelines pooled it, 1,166 citations in OpenAlex.
- Comparative long-term quality of life outcomes in adolescent idiopathic scoliosis: a meta-analysis of surgical, conservative, and observation-based strategies.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Pooled it
- Effects of bracing on pulmonary function in adolescent idiopathic scoliosis: a systematic review.BMC musculoskeletal disorders · 2026Pooled it
- Pooled it
- Short-term effectiveness of soft bracing in the treatment of adolescent idiopathic scoliosis: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Effect of Supervised Versus Hybrid Delivery of Physiotherapeutic Scoliosis-Specific Exercises in Adolescents with Idiopathic Scoliosis: Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Schroth exercises added to bracing for adolescent idiopathic scoliosis: a systematic review and meta-analysis.Frontiers in sports and active living · 2026Pooled it
- A comprehensive narrative review of scoliosis in children and adolescents: epidemiology, screening strategies, therapeutic interventions, and biomechanical research.Frontiers in pediatrics · 2026Pooled it
- Bracing effectiveness in idiopathic early onset scoliosis followed to skeletal maturity: a systematic review and meta-analysis.Spine deformity · 2025Pooled it
- Identifying predictors of brace treatment outcomes for adolescents or adults with idiopathic scoliosis: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Pooled it
- Therapeutic exercises for idiopathic scoliosis in adolescents.The Cochrane database of systematic reviews · 2024Pooled it
- A comparison between Boston brace and European braces in the treatment of adolescent idiopathic scoliosis (AIS) patients: a systematic review based on the standardised Scoliosis Research Society (SRS) inclusion criteria for brace treatment.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Pooled it
- Efficacy of a reduced brace wear regimen supported by Schroth exercise in adolescent idiopathic scoliosis: a randomized trial.Frontiers in pediatrics · 2026Trial
- Effectiveness of nighttime vs full-time bracing in the treatment of moderate-grade adolescent idiopathic scoliosis: a secondary analysis of the CONTRAIS trial.Acta orthopaedica · 2025Trial
- On mobility and gait in scoliosis patients: a comparison of conventional and 3D-printed braces during an instrumented timed-up and go test.BMC musculoskeletal disorders · 2025Trial
- Nighttime Bracing or Exercise in Moderate-Grade Adolescent Idiopathic Scoliosis: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Age matters: increased perioperative morbidity in young adults compared to adolescents undergoing posterior spinal fusion for idiopathic scoliosis.Spine deformity · 2026Article
- In-brace correction but not coronal deformity angular ratio is associated with curve progression in nighttime brace treatment for adolescent idiopathic scoliosis.Spine deformity · 2026Article
- Immediate in-brace correction and 1-year radiographic stability after a hybrid textile brace for adolescent idiopathic scoliosis: a retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Can General-purpose Multimodal AI Reliably Measure Cobb Angles? A Head-to-head Diagnostic Agreement Study of GPT-5.1 and Gemini 3.1 Pro in Adolescent Idiopathic Scoliosis.Journal of imaging informatics in medicine · 2026Article
- Radiographic and perceptual outcomes of shoulder imbalance in AIS: bracing alone versus bracing with Schroth methods.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
471 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
- Commented on by
- Commented on by
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundThe role of bracing in patients with adolescent idiopathic scoliosis who are at risk for curve progression and eventual surgery is controversial.
methodsWe conducted a multicenter study that included patients with typical indications for bracing due to their age, skeletal immaturity, and degree of scoliosis. Both a randomized cohort and a preference cohort were enrolled. Of 242 patients included in the analysis, 116 were randomly assigned to bracing or observation, and 126 chose between bracing and observation. Patients in the bracing group were instructed to wear the brace at least 18 hours per day. The primary outcomes were curve progression to 50 degrees or more (treatment failure) and skeletal maturity without this degree of curve progression (treatment success).
resultsThe trial was stopped early owing to the efficacy of bracing. In an analysis that included both the randomized and preference cohorts, the rate of treatment success was 72% after bracing, as compared with 48% after observation (propensity-score-adjusted odds ratio for treatment success, 1.93; 95% confidence interval [CI], 1.08 to 3.46). In the intention-to-treat analysis, the rate of treatment success was 75% among patients randomly assigned to bracing, as compared with 42% among those randomly assigned to observation (odds ratio, 4.11; 95% CI, 1.85 to 9.16). There was a significant positive association between hours of brace wear and rate of treatment success (P<0.001).
conclusionsBracing significantly decreased the progression of high-risk curves to the threshold for surgery in patients with adolescent idiopathic scoliosis. The benefit increased with longer hours of brace wear. (Funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases and others; BRAIST ClinicalTrials.gov number, NCT00448448.).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.