Evidence map›Paper›PMID 24047261›Full record

ArticleBMC infectious diseases2013

Modelling the impact of chlamydia screening on the transmission of HIV among men who have sex with men.

Maria Xiridou, Henrike J Vriend, Anna K Lugner, Jacco Wallinga, Johannes S Fennema, Jan M Prins, Suzanne E Geerlings, Bart J A Rijnders, Maria Prins, Henry J C de Vries and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Maria XiridouNational Institute of Public Health and Environment, P,O, Box 1, 3720, BA Bilthoven, the Netherlands. maria.xiridou@rivm.nl.
Henrike J Vriend
Anna K Lugner
Jacco Wallinga
Johannes S Fennema
Jan M Prins
Suzanne E Geerlings
Bart J A Rijnders
Maria Prins
Henry J C de Vries
Maarten J Postma
Maaike G van Veen
Maarten F Schim van der Loeff
Marianne A B van der Sande
National Institute for Public Health and the Environment · NLGGD Amsterdam · NLAcademic Medical Center · NLErasmus University Rotterdam · NLUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies have found high prevalences of asymptomatic rectal chlamydia among HIV-infected men who have sex with men (MSM). Chlamydia could increase the infectivity of HIV and the susceptibility to HIV infection. We investigate the role of chlamydia in the spread of HIV among MSM and the possible impact of routine chlamydia screening among HIV-infected MSM at HIV treatment centres on the incidence of chlamydia and HIV in the overall MSM population.

methodsA mathematical model was developed to describe the transmission of HIV and chlamydia among MSM. Parameters relating to sexual behaviour were estimated from data from the Amsterdam Cohort Study among MSM. Uncertainty analysis was carried out for model parameters without confident estimates. The effects of different screening strategies for chlamydia were investigated.

resultsAmong all new HIV infections in MSM, 15% can be attributed to chlamydia infection. Introduction of routine chlamydia screening every six months among HIV-infected MSM during regular HIV consultations can reduce the incidence of both infections among MSM: after 10 years, the relative percentage reduction in chlamydia incidence would be 15% and in HIV incidence 4%, compared to the current situation. Chlamydia screening is more effective in reducing HIV incidence with more frequent screening and with higher participation of the most risky MSM in the screening program.

conclusionsChlamydia infection could contribute to the transmission of HIV among MSM. Preventive measures reducing chlamydia prevalence, such as routine chlamydia screening of HIV-infected MSM, can result in a decline in the incidence of chlamydia and HIV.

Indexed as

AdultChlamydiaChlamydia InfectionsHIV InfectionsHomosexuality, MaleHumansMaleMass ScreeningModels, Theoretical

Identifiers

PMID24047261
PMCPMC3851177
OpenAlexW2130003325

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.