Trial reportCirculation. Heart failure2013
Targeting the kidney in acute heart failure: can old drugs provide new benefit? Renal Optimization Strategies Evaluation in Acute Heart Failure (ROSE AHF) trial.
Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph
Trial report in Circulation. Heart failure, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pharmacological interventions for heart failure in people with chronic kidney disease.The Cochrane database of systematic reviews · 2020Pooled it
- Pooled it
- Differential Response to Low-Dose Dopamine or Low-Dose Nesiritide in Acute Heart Failure With Reduced or Preserved Ejection Fraction: Results From the ROSE AHF Trial (Renal Optimization Strategies Evaluation in Acute Heart Failure).Circulation. Heart failure · 2016Trial
- Evaluation of a provocative dyspnea severity score in acute heart failure.American heart journal · 2016Trial
- Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction: the ROSE acute heart failure randomized trial.JAMA · 2013 · on this mapTrial
- The Early Pharmacological Strategy with Inodilator, bEta-blockers, Mineralocorticoid Receptor Antagonists, Sodium-glucose coTransporter-2 Inhibitors and Angiotensin Receptor-neprylisin Inhibitors in Acute Heart Failure (PENTA-HF).Current vascular pharmacology · 2025Observational
- Improvement in Renal Function During the Treatment of Acute Decompensated Heart Failure: Relationship With Markers of Renal Tubular Injury and Prognostic Importance.Circulation. Heart failure · 2023Article
- The interstitial compartment as a therapeutic target in heart failure.Frontiers in cardiovascular medicine · 2022Review
- Natriuretic Response Is Highly Variable and Associated With 6-Month Survival: Insights From the ROSE-AHF Trial.JACC. Heart failure · 2019Article
- Trajectory of Congestion Metrics by Ejection Fraction in Patients With Acute Heart Failure (from the Heart Failure Network).The American journal of cardiology · 2017Article
- Timing and Causes of Readmission After Acute Heart Failure Hospitalization-Insights From the Heart Failure Network Trials.Journal of cardiac failure · 2016Article
- Evaluation of Novel Metrics of Symptom Relief in Acute Heart Failure: The Worst Symptom Score.Journal of cardiac failure · 2016Article
- Serum Bicarbonate in Acute Heart Failure: Relationship to Treatment Strategies and Clinical Outcomes.Journal of cardiac failure · 2016Article
- Implications of Using Different Definitions on Outcomes in Worsening Heart Failure.Circulation. Heart failure · 2016Article
- Biomarkers of acute kidney injury and associations with short- and long-term outcomes.F1000Research · 2016Review
- Degeneration of Dopaminergic Neurons Due to Metabolic Alterations and Parkinson's Disease.Frontiers in aging neuroscience · 2016Review
- ROSE-AHF and lessons learned.Current heart failure reports · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Horng H ChenDepartment of Medicine, Mayo Clinic, Rochester, MN.
Omar F AbouEzzeddine
Kevin J Anstrom
Michael M Givertz
Bradley A Bart
G Michael Felker
Adrian F Hernandez
Kerry L Lee
Eugene Braunwald
Margaret M Redfield
Heart Failure Clinical Research Network
Funding
Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2MHeart Failure Clinical Research Network Coordinating CenterU10HL084904 · NHLBI · DUKE UNIVERSITY · PI ANSTROM, KEVIN J, HERNANDEZ, ADRIAN · 2012 to 2018
$38.0MAtlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8MResearch Desogn and Biostatistics CoreU54MD007588 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI JOHNSON, PRISCILLA SUE · 2012 to 2018
$24.8MMayo Heart Failure Regional Clinical CenterU10HL110262 · NHLBI · MAYO CLINIC ROCHESTER · PI REDFIELD, MARGARET M · 2012 to 2018
$3.6MHeart Failure Clinical Research Network Regional Clinical Center (U10)U10HL110312 · NHLBI · DUKE UNIVERSITY · PI FELKER, GARY M · 2012 to 2018
$3.5MSALsalate to Improve Exercise toleraNce and LVDD in T2dm-DHF (SALIENT-DHF trial)U10HL110309 · NHLBI · WASHINGTON UNIVERSITY · PI DAVILA-ROMAN, VICTOR G., MANN, DOUGLAS L · 2012 to 2018
$3.5MHarvard Regional Clinical Center of the NHLBI Heart Failure NetworkU10HL110337 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI GIVERTZ, MICHAEL M, LEWIS, GREGORY DYER · 2012 to 2018
$3.5MRenal Sympathetic Denervation in Congestive Heart FailureU10HL110336 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI STARLING, RANDALL CARSON, TANG, WAI HONG WILSON · 2012 to 2018
$2.5MHeart Failure Clinical Trials NetworkU10HL110302 · NHLBI · EMORY UNIVERSITY · PI SMITH, ANDREW · 2012 to 2018
$2.5MMayo Heart Failure Regional Clinical CenterU01HL084907 · NHLBI · MAYO CLINIC ROCHESTER · PI REDFIELD, MARGARET M · 2006 to 2011
$2.4MMid Atlantic Heart Failure NetworkU10HL110338 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CAPPOLA, THOMAS P., MARGULIES, KENNETH BER · 2012 to 2018
$2.4MNCATS NIH HHS UL1 TR000135NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1TR000454NHLBI NIH HHS U01 HL084861NHLBI NIH HHS U01 HL084889NHLBI NIH HHS U01 HL084890NHLBI NIH HHS U01HL084890NHLBI NIH HHS U01 HL084891NHLBI NIH HHS U01 HL084907NHLBI NIH HHS U01 HL084931NHLBI NIH HHS U109 HL110337NHLBI NIH HHS U10 HL084904NHLBI NIH HHS U10 HL110262NHLBI NIH HHS U10 HL110297NHLBI NIH HHS U10 HL110302NHLBI NIH HHS U10HL110302NHLBI NIH HHS U10 HL110309NHLBI NIH HHS U10 HL110312NHLBI NIH HHS U10 HL110336NHLBI NIH HHS U10 HL110337NHLBI NIH HHS U10 HL110338NHLBI NIH HHS U10 HL110342NHLBI NIH HHS U10HL110342NIMHD NIH HHS 8 U54 MD007588NIMHD NIH HHS U54 MD007588
Abstract
PubMed holds no abstract for this paper.
Indexed as
Research DesignAcute DiseaseCardiovascular AgentsClinical ProtocolsDopamineHeart FailureHumansKidneyNatriuretic Peptide, BrainRecombinant ProteinsTreatment OutcomeUnited StatesCardiovascular AgentsDopamineNatriuretic Peptide, BrainRecombinant Proteinscatecholamineheart failurenatriuretic peptides
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.