Trial reportJournal of assisted reproduction and genetics2013
The impact of semen quality, occupational exposure to environmental factors and lifestyle on recurrent pregnancy loss.
Trial report in Journal of assisted reproduction and genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A systematic review on the role of paternal factors in human placental development, function, and pregnancy-related disorders.Journal of assisted reproduction and genetics · 2025Pooled it
- Australasian recurrent pregnancy loss clinical management guideline 2024, part II.The Australian & New Zealand journal of obstetrics & gynaecology · 2024Guideline
- Relationship Among Traditional Semen Parameters, Sperm DNA Fragmentation, and Unexplained Recurrent Miscarriage: A Systematic Review and Meta-Analysis.Frontiers in endocrinology · 2021Pooled it
- Knowledge, Attitudes, and Practices Toward Unexplained Recurrent Pregnancy Loss Among Afflicted Women.Risk management and healthcare policy · 2025Article
- Preconception sleep duration, non-daytime work schedules, and incidence of spontaneous abortion: a prospective cohort study.Human reproduction (Oxford, England) · 2024Article
- A prospective cohort study of preconception COVID-19 vaccination and miscarriage.Human reproduction (Oxford, England) · 2023Article
- The Diagnostics and Treatment of Recurrent Pregnancy Loss.Journal of clinical medicine · 2023Review
- Male Contributory Factors in Recurrent Pregnancy Loss.Reproductive sciences (Thousand Oaks, Calif.) · 2023Review
- Double strand DNA breaks in sperm: the bad guy in the crowd.Journal of assisted reproduction and genetics · 2023Article
- The Role of Seminal Oxidative Stress in Recurrent Pregnancy Loss.Antioxidants (Basel, Switzerland) · 2023Review
- Sperm as a Carrier of Genome Instability in Relation to Paternal Lifestyle and Nutritional Conditions.Nutrients · 2022Article
- Male factor testing in recurrent pregnancy loss cases: A narrative review.International journal of reproductive biomedicine · 2022Review
- A Factor Analysis Model for Rapid Evaluation of the Semen Quality of Fertile Men in China.Journal of multidisciplinary healthcare · 2022Article
- DNA Methylation and Recurrent Pregnancy Loss: A Mysterious Compass?Frontiers in immunology · 2021Review
- Downregulation of testosterone production through luteinizing hormone receptor regulation in male rats exposed to 17α-ethynylestradiol.Scientific reports · 2020Article
- Influence of Lifestyle and Environmental Factors on Semen Quality in Ghanaian Men.International journal of reproductive medicine · 2020Article
- Should We Offer In Vitro Fertilization to Couples with Unexplained Recurrent Pregnancy Loss?Journal of clinical medicine · 2019Review
- C677T polymorphism increases the risk of early spontaneous abortion.Journal of assisted reproduction and genetics · 2019Article
- Seminal profile of 23,504 patients over the years: 7 years of experience.JBRA assisted reproduction · 2018Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to investigate the effect of male semen quality, occupational exposure, and lifestyle on recurrent pregnancy loss (RPL).
methodsInformation on couples' occupational exposure and lifestyle was collected using a detailed questionnaire from 68 RPL couples and 63 randomly selected healthy controls. Semen parameters were estimated by computer-assisted sperm analysis, and sperm nuclear status was detected with aniline blue (AB) staining.
resultsPatients in the RPL group had significantly lower viability, normal morphology, and total progressive motility of sperm, and a higher mean percentage of AB staining positive sperm compared with those of controls (P < 0.05). There were no differences in sperm concentration, and motility between the groups (P > 0.05). Significant odds ratio (OR) was found when occupational exposure and unhealthy habits were superimposed (OR: 11.965, P = 0.005).
conclusionsIn addition to standard female factors for evaluating the risk for RPL, the use of male factors should also be taken into consideration. We found that sperm quality, occupational exposure, and lifestyle are factors that affect RPL. Consequently, occupational exposure and lifestyle factors should constitute an important section of questionnaires given to patients, and these factors should be evaluated by a clinician or trained staff.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.