ArticlemBio2013
Canine distemper virus (CDV) in another big cat: should CDV be renamed carnivore distemper virus?
Article in mBio, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Geographical Distribution of Carnivore Hosts and Genotypes of Canine Distemper Virus (CDV) Worldwide: A Scoping Review and Spatial Meta-Analysis.Transboundary and emerging diseases · 2025Pooled it
- Diversity of susceptible hosts in canine distemper virus infection: a systematic review and data synthesis.BMC veterinary research · 2016Pooled it
- Construction and Application of a Canine SLAM Receptor-Based System from Vero Cell Line to Virus Isolation and Parallel Antibody Screening.International journal of molecular sciences · 2026Article
- Global Phylogenetic Analysis of the CDV Hemagglutinin Gene Reveals Positive Selection on Key Receptor-Binding Sites.Viruses · 2025Article
- Concurrent Rabies and Canine Distemper Outbreaks and Infection in Endangered Ethiopian Wolves.Emerging infectious diseases · 2024Article
- Feline Morbillivirus: Clinical Relevance of a Widespread Endemic Viral Infection of Cats.Viruses · 2023Review
- Comparison of some cytokines, acute phase proteins and citrulline levels in healthy and canine distemper infected dogs.The Journal of veterinary medical science · 2023Article
- Direct interaction of the molecular chaperone GRP78/BiP with the Newcastle disease virus hemagglutinin-neuraminidase protein plays a vital role in viral attachment to and infection of culture cells.Frontiers in immunology · 2023Article
- Molecular diagnosis with the corresponding clinical symptoms of canine distemper virus infection in javan leopard (Heliyon · 2022Article
- Contributions of distemper control and habitat expansion to the Amur leopard viability.Communications biology · 2022Article
- Article
- Nanoparticles of conformation-stabilized canine distemper virus hemagglutinin are highly immunogenic and induce robust immunity.Virology journal · 2021Article
- Sylvatic Canine Morbillivirus in CaptivePathogens (Basel, Switzerland) · 2021Article
- Article
- Identifying Candidate Genetic Markers of CDV Cross-Species Pathogenicity in African Lions.Pathogens (Basel, Switzerland) · 2020Article
- Characterization and Comparison of SLAM/CD150 in Free-Ranging Coyotes, Raccoons, and Skunks in Illinois for Elucidation of Canine Distemper Virus Disease.Pathogens (Basel, Switzerland) · 2020Article
- Article
- Development and validation of a portable, point-of-care canine distemper virus qPCR test.PloS one · 2020Article
- Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the greatest threats to the conservation of wild cat populations may be dogs or, at least, one of their viruses. Canine distemper virus (CDV), a single-stranded RNA virus in the Paramyxoviridae family and genus Morbillivirus, infects and causes disease in a variety of species, not just canids. An outbreak of CDV in wild lions in the Serengeti, Tanzania, in 1994 was a wake-up call for conservationists, as it demonstrated that an infectious disease could swiftly impact a previously healthy felid population. To understand how this virus causes disease in noncanid hosts, researchers have focused on specific mutations in the binding site of the CDV hemagglutinin gene. Now, Seimon et al. provide information on CDV in its latest feline victim, the endangered wild Amur tiger (Panthera tigris altaica) [T. A. Seimon et al., mBio 4(4):e00410-13, 2013, doi:10.1128/mBio.00410-13]. Their findings of CDV strains infecting tigers, in combination with recent information from other felids, paints a different picture, one in which CDV strains from a variety of geographic lineages and with a variety of amino acid residues in the hemagglutinin gene binding site can infect cats and cause disease. Although CDV has been known as a multihost disease since its discovery in domestic dogs in 1905, perhaps it is time to reconsider whether these noncanid species are not just incidental or "spillover" hosts but, rather, a normal part of the complex ecology of this infectious disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.