ArticleRespiratory medicine2013
Nitrogen dioxide and allergic sensitization in the 2005-2006 National Health and Nutrition Examination Survey.
Article in Respiratory medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Outdoor Air Pollution and Pediatric Respiratory Disease.Clinics in chest medicine · 2024Review
- Exposure to air pollution concentrations of various intensities in early life and allergic sensitisation later in childhood.BMC pulmonary medicine · 2023Article
- Air Quality Index and Emergency Department Visits and Hospitalizations for Childhood Asthma.Annals of the American Thoracic Society · 2022Article
- Digital Healthcare for Airway Diseases from Personal Environmental Exposure.Yonsei medical journal · 2022Review
- Health Effects of Ozone on Respiratory Diseases.Tuberculosis and respiratory diseases · 2020Article
- Synergistic Association of House Endotoxin Exposure and Ambient Air Pollution with Asthma Outcomes.American journal of respiratory and critical care medicine · 2019Article
- Associations of gestational and the first year of life exposure to ambient air pollution with childhood eczema in Hubei, China.Environmental science and pollution research international · 2019Article
- Air Pollutants are associated with Dry Eye Disease in Urban Ophthalmic Outpatients: a Prevalence Study in China.Journal of translational medicine · 2019Article
- Urinary polycyclic aromatic hydrocarbons and allergic sensitization in a nationwide study of children and adults in the United States.The Journal of allergy and clinical immunology · 2018Article
- Preventive Effect of Residential Green Space on Infantile Atopic Dermatitis Associated with Prenatal Air Pollution Exposure.International journal of environmental research and public health · 2018Article
- Maternal Exposure of BALB/c Mice to Indoor NO2 and Allergic Asthma Syndrome in Offspring at Adulthood with Evaluation of DNA Methylation Associated Th2 Polarization.Environmental health perspectives · 2017Article
- Concentration-dependent effects of PMEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017Article
- Allergic disease associations with regional and localized estimates of air pollution.Environmental research · 2017Article
- Air Pollution and Preterm Birth in the U.S. State of Georgia (2002-2006): Associations with Concentrations of 11 Ambient Air Pollutants Estimated by Combining Community Multiscale Air Quality Model (CMAQ) Simulations with Stationary Monitor Measurements.Environmental health perspectives · 2016Article
- Pediatric Emergency Visits and Short-Term Changes in PM2.5 Concentrations in the U.S. State of Georgia.Environmental health perspectives · 2016Article
- Environmental effects on immune responses in patients with atopy and asthma.The Journal of allergy and clinical immunology · 2014Review
- Prevalence of allergic sensitization in the United States: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006.The Journal of allergy and clinical immunology · 2014Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundAllergic sensitization is a risk factor for asthma and allergic diseases. The relationship between ambient air pollution and allergic sensitization is unclear.
objectiveTo investigate the relationship between ambient air pollution and allergic sensitization in a nationally representative sample of the US population.
methodsWe linked annual average concentrations of nitrogen dioxide (NO2), particulate matter ≤10 μm (PM10), particulate matter ≤2.5 μm (PM2.5), and summer concentrations of ozone (O3), to allergen-specific immunoglobulin E (IgE) data for participants in the 2005-2006 National Health and Nutrition Examination Survey (NHANES). In addition to the monitor-based air pollution estimates, we used the Community Multiscale Air Quality (CMAQ) model to increase the representation of rural participants in our sample. Logistic regression with population-based sampling weights was used to calculate adjusted prevalence odds ratios per 10 ppb increase in O3 and NO2, per 10 μg/m(3) increase in PM10, and per 5 μg/m(3) increase in PM2.5 adjusting for race, gender, age, socioeconomic status, smoking, and urban/rural status.
resultsUsing CMAQ data, increased levels of NO2 were associated with positive IgE to any (OR 1.15, 95% CI 1.04, 1.27), inhalant (OR 1.17, 95% CI 1.02, 1.33), and indoor (OR 1.16, 95% CI 1.03, 1.31) allergens. Higher PM2.5 levels were associated with positivity to indoor allergen-specific IgE (OR 1.24, 95% CI 1.13, 1.36). Effect estimates were similar using monitored data.
conclusionsIncreased ambient NO2 was consistently associated with increased prevalence of allergic sensitization.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.