ArticleThe Plant cell2013
Expression quantitative trait locus mapping across water availability environments reveals contrasting associations with genomic features in Arabidopsis.
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Genotype by Environment Interactions in Gene Regulation Underlie the Response to Soil Drying in the Model Grass Brachypodium distachyon.Molecular biology and evolution · 2025Article
- The quantitative genetics of gene expression in Mimulus guttatus.PLoS genetics · 2024Article
- Combined genome-wide association studies and expression quantitative trait locus analysis uncovers a genetic regulatory network of floral organ number in a tree peony (Horticulture research · 2023Article
- Prioritizing candidate eQTL causal genes in Arabidopsis using RANDOM FORESTS.G3 (Bethesda, Md.) · 2022Article
- Article
- A Pleiotropic Flowering Time QTL Exhibits Gene-by-Environment Interaction for Fitness in a Perennial Grass.Molecular biology and evolution · 2022Article
- Genetics as a key to improving crop photosynthesis.Journal of experimental botany · 2022Article
- SPARSE MATRIX LINEAR MODELS FOR STRUCTURED HIGH-THROUGHPUT DATA.The annals of applied statistics · 2022Article
- Natural variation in growth and leaf ion homeostasis in response to salinity stress inFrontiers in plant science · 2022Article
- Exploitation of Drought Tolerance-Related Genes for Crop Improvement.International journal of molecular sciences · 2021Review
- Fine-scale empirical data on niche divergence and homeolog expression patterns in an allopolyploid and its diploid progenitor species.The New phytologist · 2021Article
- Article
- Network Analysis PrioritizesG3 (Bethesda, Md.) · 2020Article
- Genome-wide expression quantitative trait locus analysis in a recombinant inbred line population for trait dissection in peanut.Plant biotechnology journal · 2020Article
- Discovery of early life stress interacting and sex-specific quantitative trait loci impacting cocaine responsiveness.British journal of pharmacology · 2019Article
- Components of Water Use Efficiency Have Unique Genetic Signatures in the Model CPlant physiology · 2018Article
- Integrated QTL and eQTL Mapping Provides Insights and Candidate Genes for Fatty Acid Composition, Flowering Time, and Growth Traits in a FFrontiers in plant science · 2018Article
- In situ conservation-harnessing natural and human-derived evolutionary forces to ensure future crop adaptation.Evolutionary applications · 2017Review
- Time-course expression QTL-atlas of the global transcriptional response of wheat to Fusarium graminearum.Plant biotechnology journal · 2017Article
- Stress-Related Gene Expression Reflects Morphophysiological Responses to Water Deficit.Plant physiology · 2017Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The regulation of gene expression is crucial for an organism's development and response to stress, and an understanding of the evolution of gene expression is of fundamental importance to basic and applied biology. To improve this understanding, we conducted expression quantitative trait locus (eQTL) mapping in the Tsu-1 (Tsushima, Japan) × Kas-1 (Kashmir, India) recombinant inbred line population of Arabidopsis thaliana across soil drying treatments. We then used genome resequencing data to evaluate whether genomic features (promoter polymorphism, recombination rate, gene length, and gene density) are associated with genes responding to the environment (E) or with genes with genetic variation (G) in gene expression in the form of eQTLs. We identified thousands of genes that responded to soil drying and hundreds of main-effect eQTLs. However, we identified very few statistically significant eQTLs that interacted with the soil drying treatment (GxE eQTL). Analysis of genome resequencing data revealed associations of several genomic features with G and E genes. In general, E genes had lower promoter diversity and local recombination rates. By contrast, genes with eQTLs (G) had significantly greater promoter diversity and were located in genomic regions with higher recombination. These results suggest that genomic architecture may play an important a role in the evolution of gene expression.
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