Evidence map›Paper›PMID 24043743›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2013

Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma.

Nienke van Rooij, Marit M van Buuren, Daisy Philips, Arno Velds, Mireille Toebes, Bianca Heemskerk, Laura J A van Dijk, Sam Behjati, Henk Hilkmann, Dris El Atmioui and 7 more

2 registry-linked trialsAbstract readCase Reports
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 509 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
509citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02963090 phase2terminatednot on this mapstarted 2017, after this paper: background citation

A Randomized Phase II Study Evaluating Pembrolizumab vs Topotecan in the Second-Line Treatment of Patients With Small Cell Lung Cancer

TypeinterventionalSponsorAlliance Foundation Trials, LLC.Ran2017 to 2019Enrolled9ConditionsSmall Cell Lung CancerArmsTopotecan, Pembrolizumab
NCT04165967 phase1completednot on this mapstarted 2020, after this paper: background citation

A Phase I Study of Adoptive Tumor-infiltrating Lymphocyte Transfer in Combination With Nivolumab in Patients With Advanced Melanoma

TypeinterventionalSponsorUniversity Hospital, Basel, SwitzerlandRan2020 to 2023Enrolled9ConditionsAdvanced MelanomaArmsCombination of TIL Transfer with anti-PD-1 Therapy and low dose IL-2
3 · Its place in the literature

Who cites it

509 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  17. Current issues in molecular biology · 2025
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449 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Nienke van RooijNetherlands Cancer Institute, Amsterdam, the Netherlands.
Marit M van Buuren
Daisy Philips
Arno Velds
Mireille Toebes
Bianca Heemskerk
Laura J A van Dijk
Sam Behjati
Henk Hilkmann
Dris El Atmioui
Marja Nieuwland
Michael R Stratton
Ron M Kerkhoven
Can Kesmir
John B Haanen
Pia Kvistborg
Ton N Schumacher

Funding

Wellcome Trust 098051
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ExomeAntibodies, MonoclonalAntigens, NeoplasmAntineoplastic AgentsDNA, NeoplasmHumansIpilimumabLymphocytes, Tumor-InfiltratingMaleMelanomaMiddle AgedSkin NeoplasmsT-LymphocytesAntibodies, MonoclonalAntigens, NeoplasmAntineoplastic AgentsDNA, NeoplasmIpilimumab

Identifiers

PMID24043743
PMCPMC3836220

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.