ArticleThe American journal of tropical medicine and hygiene2013
Dried blood spots for qPCR diagnosis of acute Bartonella bacilliformis infection.
Article in The American journal of tropical medicine and hygiene, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Molecular Characterization of Fluoroquinolone-ResistantPathogens (Basel, Switzerland) · 2021Article
- High prevalence and diversity of Bartonella in small mammals from the biodiverse Western Ghats.PLoS neglected tropical diseases · 2021Article
- Carrion's Disease: the Sound of Silence.Clinical microbiology reviews · 2018Review
- Immunosuppressive and angiogenic cytokine profile associated with Bartonella bacilliformis infection in post-outbreak and endemic areas of Carrion's disease in Peru.PLoS neglected tropical diseases · 2017Article
- Succinyl-CoA Synthetase: New Antigen Candidate of Bartonella bacilliformis.PLoS neglected tropical diseases · 2016Article
- Evaluation of PCR Approaches for Detection of Bartonella bacilliformis in Blood Samples.PLoS neglected tropical diseases · 2016Article
- Oroya fever and verruga peruana: bartonelloses unique to South America.PLoS neglected tropical diseases · 2014Review
- Diagnosis of Carrion's disease by direct blood PCR in thin blood smear negative samples.PloS one · 2014Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bartonella bacilliformis is the etiological agent of a life-threatening illness. Thin blood smear is the most common diagnostic method for acute infection in endemic areas of Peru but remains of limited value because of low sensitivity. The aim of this study was to adapt a B. bacilliformis-specific real-time polymerase chain reaction (PCR) assay for use with dried blood spots (DBS) as a sampling method and assess its performance and use for the diagnosis and surveillance of acute Bartonella infection. Only two of 65 children (3%) that participated in this study had positive blood smears for B. bacilliformis, whereas 16 (including these two) were positive by PCR performed on DBS samples (24.6%). The use of DBS in combination with B. bacilliformis-specific PCR could be a useful tool for public health in identifying and monitoring outbreaks of infection and designing control programs to reduce the burden of this life-threatening illness.
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