ArticleJournal of the American Society for Mass Spectrometry2013
Simulation of rarefied gas flows in atmospheric pressure interfaces for mass spectrometry systems.
Article in Journal of the American Society for Mass Spectrometry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 26 citations in OpenAlex.
- Hybrid CFD-DSMC Simulation of Ion Transport in Photoionization Mass Spectrometry: From Atmospheric Pressure to High Vacuum.Rapid communications in mass spectrometry : RCM · 2026Article
- Direct Analysis of Organic Compounds in Liquid Using a Miniature Photoionization Ion Trap Mass Spectrometer with Pulsed Carrier-Gas Capillary Inlet.Journal of the American Society for Mass Spectrometry · 2017Article
- Miniature and Fieldable Mass Spectrometers: Recent Advances.Analytical chemistry · 2016Review
- Numerical analysis of ion-funnel transmission efficiency in an API-MS system with a continuum/microscopic approach.Journal of the American Society for Mass Spectrometry · 2015Article
- On an aerodynamic mechanism to enhance ion transmission and sensitivity of FAIMS for nano-electrospray ionization-mass spectrometry.Journal of the American Society for Mass Spectrometry · 2014Article
- Flowing gas in mass spectrometer: method for characterization and impact on ion processing.The Analyst · 2014Article
- Development of miniature mass spectrometry systems for bioanalysis outside the conventional laboratories.Bioanalysis · 2014Article
- Ion sponge: a 3-dimentional array of quadrupole ion traps for trapping and mass-selectively processing ions in gas phase.Analytical chemistry · 2014Article
- Numerical modeling of ion transport in an ESI-MS system.Journal of the American Society for Mass Spectrometry · 2014Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The understanding of the gas dynamics of the atmospheric pressure interface is very important for the development of mass spectrometry systems with high sensitivity. While the gas flows at high pressure (>1 Torr) and low pressure (<10(-3) Torr) stages are relatively well understood and could be modeled using continuum and molecular flows, respectively, the theoretical modeling or numeric simulation of gas flow through the transition pressure stage (1 to 10(-3) Torr) remains challenging. In this study, we used the direct simulation Monte Carlo (DMSC) method to develop the gas dynamic simulations for the continuous and discontinuous atmospheric pressure interfaces (API), with different focuses on the ion transfer by gas flows through a skimmer or directly from the atmospheric pressure to a vacuum stage, respectively. The impacts by the skimmer location in the continuous API and the temporal evolvement of the gas flow with a discontinuous API were characterized, which provide a solid base for the instrument design and performance improvement.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.