Trial reportClinical oral investigations2014
A randomized clinical trial on the use of medical Portland cement, MTA and calcium hydroxide in indirect pulp treatment.
Trial report in Clinical oral investigations, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Split-mouth Trial Comparing Biodentine and Calcium Hydroxide in the Indirect Pulp Treatment on Primary Teeth
Antibacterial Effect of Light-activated Calcium Silicate Versus Calcium Hydroxide on Permanent Carious Molars Treated With Step-wise Excavation (A Randomized Clinical Trial)
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Deep caries management: EFCD-ESE-ORCA S3-level clinical practice guideline.Clinical oral investigations · 2026Guideline
- Deep Caries Management: EFCD-ESE-ORCA S3-Level Clinical Practice Guideline.Caries research · 2026Guideline
- Clinical outcomes of selective removal to soft dentin versus firm dentin for deep caries lesions: a randomized controlled trial up to 5 years.Clinical oral investigations · 2024Trial
- Direct pulp capping in asymptomatic carious primary molars using three different pulp capping materials: a prospective clinical trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2022Trial
- A randomized clinical trial of cavity liners after selective caries removal: one-year follow-up.Journal of applied oral science : revista FOB · 2019Trial
- Evaluation of the efficacy of calcium silicate vs. glass ionomer cement indirect pulp capping and restoration assessment criteria: a randomised controlled clinical trial-2-year results.Clinical oral investigations · 2019Trial
- Clinical and radiographic evaluation of Portland cement added to radiopacifying agents in primary molar pulpotomies.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2015Trial
- Postoperative Pain and Matrix Metalloproteinase-9 Pulpal Blood Level in Symptomatic Pulpitis of Mature Molars Treated with Biodentine and Portland Cement Full Pulpotomy: A Randomized Clinical Trial.Journal of clinical and experimental dentistry · 2026Review
- Comparative Evaluation of Mineral Trioxide Aggregate and Bioceramic Putty for Indirect Pulp Capping in Primary Molars: AnInternational journal of clinical pediatric dentistry · 2026Article
- Evaluation of ozonoid olive oil as an indirect pulp capping agent in permanent molars: A randomized clinical trial.Journal of conservative dentistry and endodontics · 2025Article
- Clinical and Radiographic Evaluation of Indirect Pulp Capping with Mineral Trioxide Aggregate and Calcium Hydroxide in Primary Molars: A Systematic Review and Meta-analysis.International journal of clinical pediatric dentistry · 2025Article
- Review
- Comparison between biodentine and light-cured mineral trioxide aggregate as an indirect pulp capping agent - A randomized controlled trial.Journal of conservative dentistry and endodontics · 2025Article
- Calcium Silicate-Based Cements in Restorative Dentistry: Vital Pulp Therapy Clinical, Radiographic, and Histological Outcomes on Deciduous and Permanent Dentition-A Systematic Review and Meta-Analysis.Materials (Basel, Switzerland) · 2024Review
- Impact of corticosteroid administration on the response of exposed dental pulp to capping with bioactive cements-experimental study on mongrel dogs.BMC oral health · 2023Article
- A prospective clinical study with one year follow up of deep caries management using a novel biomaterial.BMC research notes · 2022Article
- Effectiveness of Direct Pulp Capping Bioactive Materials in Dentin Regeneration: A Systematic Review.Materials (Basel, Switzerland) · 2021Review
- The Effect of Calcium-Silicate Cements on Reparative Dentinogenesis Following Direct Pulp Capping on Animal Models.Molecules (Basel, Switzerland) · 2021Review
- Efficacy of different calcium silicate materials as pulp-capping agents: Randomized clinical trial.Journal of dental sciences · 2021Article
- Pulp liner materials in selective caries removal: study protocol for a randomised controlled trial.BMJ open · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesStudies on indirect pulp treatment (IPT) show varying success rates of 73 to 97 %. The necessity of re-opening the cavity and the question of the optimal capping material is still under debate. The aim of this prospective in vivo study was to compare the clinical and microbiological outcomes of mineral trioxide aggregate (MTA), medical Portland cement, and calcium hydroxide on the dentin-pulp complex of permanent and primary teeth treated with two-step IPT. MATERIALS AND
methodsIn 86 regular patients (51 % men; 49 % women; age 17.2 years ±13.8), one deep carious lesion each was treated with incomplete caries removal, randomly selected capping with either calcium hydroxide (n = 31), medical Portland cement (29) or white MTA (26), and re-entry (6.3 months ±1.0). Clinical (color, humidity, and consistency of dentin) and microbiological (Lactobacilli/Mutans Strep. counts) parameters were recorded at the first and second treatment.
resultsThe IPT had a high success rate of 90.3 % regardless of the material used (p = 0.72). The arrested lesions showed consistently darker, dry, and therefore, sclerotic dentine (p < 0.05) as well as a decrease in bacterial counts at re-entry (Lactobacilli p = 0.01/Mutans Strep. p = 0.07).
conclusionsThe findings of this study support the use of the IPT as a treatment for deep carious lesions preferably with non-resorbing materials such as MTA or medical Portland cement. CLINICAL RELEVANCE: The findings of this study could promote the improvement of the IPT as a one-step treatment of deep carious lesions when the remaining demineralized dentin would be sealed with durable restorations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.