ArticlePlant physiology2013
Feedback inhibition of starch degradation in Arabidopsis leaves mediated by trehalose 6-phosphate.
Article in Plant physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.
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99 citing papers in PubMed, 208 citations in OpenAlex.
- Stomatal movement as an emergent property of the remarkable plasticity of guard cells.The New phytologist · 2026Article
- Systemic and Local Regulation of Root Growth by Vascular Trehalose 6-Phosphate is Correlated With Re-allocation of Primary Metabolites Between Shoots and Roots.Plant, cell & environment · 2026Article
- Integrated metabolomics and transcriptomics reveal sugar metabolism associated with cold tolerance in chrysanthemum.BMC plant biology · 2026Article
- Metagenomic sequencing and binning reveal carbon cycling microorganisms and gene functions in park environments.BMC microbiology · 2026Article
- The sucrose-trehalose 6-phosphate nexus: what's next for plant vigour and productivity?Journal of experimental botany · 2026Review
- The sucrose-trehalose 6-phosphate nexus is conserved in flowering plants with different phloem loading and carbon storage strategies.Journal of experimental botany · 2026Article
- Trehalose 6-phosphate - a central regulator at the crossroads of sugar signalling, metabolism, and development.The New phytologist · 2025Review
- Blue light-induced stomatal opening is associated with species-specific changes in primary metabolism but not with starch breakdown in guard cells.The New phytologist · 2025Article
- Intercellular compartmentation of trehalose 6-phosphate metabolism in Setaria viridis leaves.Journal of experimental botany · 2025Article
- Nectary starch degradation affects nectar chemical composition, but not nectar sugars, in Arabidopsis thaliana.Plant physiology · 2025Article
- Genome-Wide Analysis of Trehalose-6-Phosphate Phosphatases (TPP) Gene Family in Potato (Plants (Basel, Switzerland) · 2025Article
- Mutations in the floral regulator gene HUA2 restore flowering to the Arabidopsis trehalose 6-phosphate synthase1 (tps1) mutant.Plant physiology · 2025Article
- The synthesis, degradation and biological function of trehalose- 6-phosphate.Stress biology · 2025Review
- RNA-seq Analysis of the Mechanisms Underlying Chalky Grain and Characterization of Two IAA Receptor Proteins OsAFB3 and OsAFB5 in Chalkiness Formation in Oryza sativa.Rice (New York, N.Y.) · 2025Article
- Article
- A LTR retrotransposon insertion leads to leafy phenotype in maize by elevating ZmOM66 expression.Nature communications · 2025Article
- A Periodic 4-h Extension of the Dark Period Did Not Cause Long-Term Changes in the Circadian Regulation of Photosynthesis and Sugar Levels in Lettuces.Plant direct · 2025Article
- Trehalose-6-phosphate synthase gene expression analysis under abiotic and biotic stresses in bottle gourd (Lagenaria siceraria).Scientific reports · 2025Article
- Starch metabolism in guard cells: At the intersection of environmental stimuli and stomatal movement.Plant physiology · 2024Review
- Direct and indirect responses of the Arabidopsis transcriptome to an induced increase in trehalose 6-phosphate.Plant physiology · 2024Article
39 more citing papers are in PubMed but not listed here.
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many plants accumulate substantial starch reserves in their leaves during the day and remobilize them at night to provide carbon and energy for maintenance and growth. In this paper, we explore the role of a sugar-signaling metabolite, trehalose-6-phosphate (Tre6P), in regulating the accumulation and turnover of transitory starch in Arabidopsis (Arabidopsis thaliana) leaves. Ethanol-induced overexpression of trehalose-phosphate synthase during the day increased Tre6P levels up to 11-fold. There was a transient increase in the rate of starch accumulation in the middle of the day, but this was not linked to reductive activation of ADP-glucose pyrophosphorylase. A 2- to 3-fold increase in Tre6P during the night led to significant inhibition of starch degradation. Maltose and maltotriose did not accumulate, suggesting that Tre6P affects an early step in the pathway of starch degradation in the chloroplasts. Starch granules isolated from induced plants had a higher orthophosphate content than granules from noninduced control plants, consistent either with disruption of the phosphorylation-dephosphorylation cycle that is essential for efficient starch breakdown or with inhibition of starch hydrolysis by β-amylase. Nonaqueous fractionation of leaves showed that Tre6P is predominantly located in the cytosol, with estimated in vivo Tre6P concentrations of 4 to 7 µm in the cytosol, 0.2 to 0.5 µm in the chloroplasts, and 0.05 µm in the vacuole. It is proposed that Tre6P is a component in a signaling pathway that mediates the feedback regulation of starch breakdown by sucrose, potentially linking starch turnover to demand for sucrose by growing sink organs at night.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.