Evidence map›Paper›PMID 24042202›Full record

ReviewCellular and molecular life sciences : CMLS2014

If the cap fits, wear it: an overview of telomeric structures over evolution.

Nick Fulcher, Elisa Derboven, Sona Valuchova, Karel Riha

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. The evolution of metazoan shelterin.Genes & development · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Molecular characterization ofLife science alliance · 2019
    Article
  13. Article
  14. Article
  15. Review
  16. Understanding diversity in telomere dynamics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018
    Article
  17. Review
  18. Article
  19. Telomerase lost?Chromosoma · 2016
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nick FulcherGregor Mendel Institute, Austrian Academy of Sciences, Dr. Bohrgasse 3, 1030, Vienna, Austria.
Elisa Derboven
Sona Valuchova
Karel Riha

Funding

Austrian Science Fund FWF Y 418
6 · The paper itself

Abstract

Genome organization into linear chromosomes likely represents an important evolutionary innovation that has permitted the development of the sexual life cycle; this process has consequently advanced nuclear expansion and increased complexity of eukaryotic genomes. Chromosome linearity, however, poses a major challenge to the internal cellular machinery. The need to efficiently recognize and repair DNA double-strand breaks that occur as a consequence of DNA damage presents a constant threat to native chromosome ends known as telomeres. In this review, we present a comparative survey of various solutions to the end protection problem, maintaining an emphasis on DNA structure. This begins with telomeric structures derived from a subset of prokaryotes, mitochondria, and viruses, and will progress into the typical telomere structure exhibited by higher organisms containing TTAGG-like tandem sequences. We next examine non-canonical telomeres from Drosophila melanogaster, which comprise arrays of retrotransposons. Finally, we discuss telomeric structures in evolution and possible switches between canonical and non-canonical solutions to chromosome end protection.

Indexed as

Evolution, MolecularModels, MolecularNucleic Acid ConformationAnimalsChromosomesDNANuclear ProteinsTelomeraseTelomereTelomere HomeostasisDNANuclear ProteinsTelomeraseterminin

Identifiers

PMID24042202
PMCPMC11113737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.