ArticleEnvironment international2013
Concentrations of urinary 8-hydroxy-2'-deoxyguanosine and 8-isoprostane in women exposed to woodsmoke in a cookstove intervention study in San Marcos, Peru.
Article in Environment international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 50 citations in OpenAlex.
- Improving household air, drinking water and hygiene in rural Peru: a community-randomized-controlled trial of an integrated environmental home-based intervention package to improve child health.International journal of epidemiology · 2016Trial
- Effect of low-cost kitchen with improved cookstove on birthweight of neonates in Shahjadpur, Bangladesh: a cluster-randomised controlled trial.The Lancet regional health. Southeast Asia · 2024Article
- Indoor (residential) and ambient particulate matter associations with urinary oxidative stress biomarkers in a COPD cohort.The Science of the total environment · 2023Article
- Assessment of Oxidative DNA Damages in Radiography Staff via Evaluation of Its Urinary Biomarker (8-hydroxy2-deoxyguanosine).International journal of preventive medicine · 2020Article
- Chemical Biomarkers of Exposure and Early Damage from Potentially Carcinogenic Airborne Pollutants.Annals of cancer epidemiology · 2019Article
- Quenching the fires: Pro-resolving mediators, air pollution, and smoking.Pharmacology & therapeutics · 2019Review
- Effects of PMSaudi journal of biological sciences · 2019Article
- Indoor black carbon of outdoor origin and oxidative stress biomarkers in patients with chronic obstructive pulmonary disease.Environment international · 2018Article
- Review
- Antioxidant defense and oxidative damage vary widely among high-altitude residents.American journal of human biology : the official journal of the Human Biology Council · 2017Article
- Exposure to polycyclic aromatic hydrocarbons and volatile organic compounds among recently pregnant rural Guatemalan women cooking and heating with solid fuels.International journal of hygiene and environmental health · 2017Article
- Aging with higher fractional exhaled nitric oxide levels are associated with increased urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine concentrations in elder females.Environmental science and pollution research international · 2016Article
- Mutagenicity and Pollutant Emission Factors of Solid-Fuel Cookstoves: Comparison with Other Combustion Sources.Environmental health perspectives · 2016Article
- Measured Pulmonary and Systemic Markers of Inflammation and Oxidative Stress Following Wildland Firefighter Simulations.Journal of occupational and environmental medicine · 2016Article
- Effectiveness of interventions to reduce indoor air pollution and/or improve health in homes using solid fuel in lower and middle income countries: protocol for a systematic review.Systematic reviews · 2015Article
- A review of PAH exposure from the combustion of biomass fuel and their less surveyed effect on the blood parameters.Environmental science and pollution research international · 2015Review
- Behavioral attitudes and preferences in cooking practices with traditional open-fire stoves in Peru, Nepal, and Kenya: implications for improved cookstove interventions.International journal of environmental research and public health · 2014Article
- Oxidative stress of office workers relevant to tobacco smoking and inner air quality.International journal of environmental research and public health · 2014Article
- Article
- [Environmental pollution, climate variability and climate change: a review of health impacts on the Peruvian population].Revista peruana de medicina experimental y salud publicaArticle
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Authors and funding
12 authors at 5 institutions in 3 countries.
Funding
Abstract
Nearly half of the world's population is exposed to household air pollution (HAP) due to long hours spent in close proximity to unvented cooking fires. The effect of woodsmoke exposure on oxidative stress was examined by investigating the association between woodsmoke exposure and biomarkers of DNA oxidation (8-hydroxy-2'-deoxyguanosine [8-OHdG]) and lipid peroxidation (8-isoprostane) among control and intervention stove users. HAP exposure assessment was conducted within the framework of a community-randomized controlled trial of 51 communities in San Marcos Province, Cajamarca Region, Peru. The first morning urine voids after 48h HAP exposure assessment from a subset of 45 control and 39 intervention stove users were analyzed for 8-OHdG and 8-isoprostane. General linear models and correlation analyses were performed. Urinary oxidative stress biomarkers ranged from 11.2 to 2270.0μg/g creatinine (median: 132.6μg/g creatinine) for 8-OHdG and from 0.1 to 4.5μg/g creatinine (median: 0.8μg/g creatinine) for 8-isoprostane among all study subjects (n=84). After controlling for the effects of traffic in the community and eating food exposed to fire among all subjects, cooking time was weakly, but positively associated with urinary 8-OHdG (r=0.29, p=0.01, n=80). Subjects' real-time personal CO exposures were negatively associated with 8-OHdG, particularly the maximum 30-second CO exposure during the sampling period (r=-0.32, p=0.001, n=73). 48h time integrated personal PM2.5 was negatively, but marginally associated with urinary 8-isoprostane (r=-0.21, p=0.09, n=69) after controlling for the effect of distance of homes to the road. Urinary 8-isoprostane levels reported in the available literature are comparable to results found in the current study. However there were relatively high levels of urinary 8-OHdG compared to data in the available literature for 8-OHdG excretion. Results suggest a sustained systemic oxidative stress among these Peruvian women chronically exposed to wood smoke.
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