Evidence map›Paper›PMID 24041230›Full record

ArticleJournal of consulting and clinical psychology2014

Treating co-occurring depression and anxiety: modeling the dynamics of psychopathology and psychotherapy using the time-varying effect model.

Aidan G C Wright, Michael N Hallquist, Holly A Swartz, Ellen Frank, Jill M Cyranowski

Open access · greenAbstract read
In one paragraph

Article in Journal of consulting and clinical psychology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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  12. Time-varying effect modeling to address new questions in behavioral research: Examples in marijuana use.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Aidan G C WrightDepartment of Psychology, University of Pittsburgh.
Michael N HallquistDepartment of Psychiatry, University of Pittsburgh School of Medicine.
Holly A SwartzDepartment of Psychiatry, University of Pittsburgh School of Medicine.
Ellen FrankDepartment of Psychiatry, University of Pittsburgh School of Medicine.
Jill M CyranowskiDepartment of Psychiatry, University of Pittsburgh School of Medicine.
University of Pittsburgh · US

Funding

CLINICAL RESEARCH TRAINING FOR PSYCHOLOGISTST32MH018269 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MICHELE D LEVINE · 1986 to 2026
$6.3M
Personalizing First-Line Treatment for Depression Complicated by Panic FeaturesR01MH085874 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CYRANOWSKI, JILL M · 2009 to 2010
$887k
Neurodevelopmental Origins of Emotion Dysregulation in Borderline PersonalityK01MH097091 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HALLQUIST, MICHAEL NELSON · 2013 to 2016
$620k
A Novel Therapy for Depression with Co-Occurring PanicR21MH061948 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FRANK, ELLEN · 2001 to 2003
$561k
Refining Borderline Personality Disorder Using Flexible Latent Variable ModelingF32MH090629 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HALLQUIST, MICHAEL NELSON · 2010 to 2011
$103k
NIMH NIH HHS F32 MH090629NIMH NIH HHS F32MH090629NIMH NIH HHS K01 MH097091NIMH NIH HHS R01 MH085874NIMH NIH HHS R01MH085874NIMH NIH HHS R21 MH061948NIMH NIH HHS R21MH061948NIMH NIH HHS T32 MH018269NIMH NIH HHS T32MH018269
6 · The paper itself

Abstract

objectiveWe demonstrate the utility of the time-varying effect model (TVEM) for the analysis of psychotherapy data, with the aim of elucidating complex patterns of change over time and dynamic associations between constructs of interest. Specifically, we examine the association between depression and co-occurring anxiety in a sample of adults treated with interpersonal psychotherapy (IPT) for depression or a variant designed to address both depression and co-occurring anxiety (IPT-PS, IPT for depression with panic and anxiety symptoms).

methodSeventy-eight (82% female) adult outpatients with major depression and co-occurring anxiety were assessed at each of 16 outpatient treatment sessions using the Hamilton rating scales for depression and anxiety.

resultsOn average, depressive symptoms declined in a quadratic form over the course of treatment. While the association between anxiety and depression was modest early in treatment, it strengthened over the middle and latter treatment phases. Finally, exploratory analyses suggest that while IPT and IPT-PS were similarly effective in reducing depressive symptoms, IPT-PS may be more effective at uncoupling the association between core anxiety and depressive symptoms.

conclusionsFindings point to the utility of the TVEM for psychotherapy research and the importance of assessing anxiety in the course of treating depression, especially following the initial phase of treatment (i.e., after Session 5).

Indexed as

Cognitive Behavioral TherapyModels, StatisticalAdultAmbulatory CareAnxietyComorbidityDepressionFemaleHumansMajor Depressive DisorderMiddle AgedOutpatientsPsychopathologyTime FactorsTreatment Outcome

Identifiers

PMID24041230
PMCPMC3955740
OpenAlexW2101714177

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.