ArticleNeuropsychology2013
Estimating the passage of minutes: deviant oscillatory frontal activity in medicated and unmedicated ADHD.
Article in Neuropsychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- The neural oscillations serving task switching are altered in cannabis users.Journal of psychopharmacology (Oxford, England) · 2024Article
- Time Perception in Adult ADHD: Findings from a Decade-A Review.International journal of environmental research and public health · 2023Review
- Atypical resting-state gamma band trajectory in adult attention deficit/hyperactivity disorder.Journal of neural transmission (Vienna, Austria : 1996) · 2021Article
- Time Perception is a Focal Symptom of Attention-Deficit/Hyperactivity Disorder in Adults.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- A novel approach to intra-individual performance variability in ADHD.European child & adolescent psychiatry · 2021Article
- Updates in technology-based interventions for attention deficit hyperactivity disorder.Current opinion in psychiatry · 2020Review
- Local cortical thickness predicts somatosensory gamma oscillations and sensory gating: A multimodal approach.NeuroImage · 2020Article
- Neural Responses to Reward in a Gambling Task: Sex Differences and Individual Variation in Reward-Driven Impulsivity.Cerebral cortex communications · 2020Article
- Deep Learning Based on Event-Related EEG Differentiates Children with ADHD from Healthy Controls.Journal of clinical medicine · 2019Article
- Neurophysiological mechanisms of interval timing dissociate inattentive and combined ADHD subtypes.Scientific reports · 2018Article
- Altered Neural Oscillations During Multisensory Integration in Adolescents with Fetal Alcohol Spectrum Disorder.Alcoholism, clinical and experimental research · 2017Article
- Linking ADHD to the Neural Circuitry of Attention.Trends in cognitive sciences · 2017Review
- Neuroimaging with magnetoencephalography: A dynamic view of brain pathophysiology.Translational research : the journal of laboratory and clinical medicine · 2016Review
- Differences in the performance of NK1R-/- ('knockout') and wildtype mice in the 5‑Choice Continuous Performance Test.Behavioural brain research · 2016Article
- Article
- Understanding schizophrenia as a disorder of consciousness: biological correlates and translational implications from quantum theory perspectives.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2015Article
- Pharmaco-MEG evidence for attention related hyper-connectivity between auditory and prefrontal cortices in ADHD.Psychiatry research · 2014Article
- Neural synchrony examined with magnetoencephalography (MEG) during eye gaze processing in autism spectrum disorders: preliminary findings.Journal of neurodevelopmental disorders · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveAttention-deficit/hyperactivity disorder (ADHD) is a common and extensively treated psychiatric disorder in children, which often persists into adulthood. The core diagnostic symptoms include inappropriate levels of hyperactivity, impulsivity, and/or pervasive inattention. Another crucial aspect of the disorder involves aberrations in temporal perception, which have been well documented in behavioral studies and, recently, have been the focus of neuroimaging studies. These functional magnetic resonance imaging studies have shown reduced activation in anterior cingulate and prefrontal cortices in ADHD using a time-interval discrimination task, whereby participants distinguish intervals differing by only hundreds of milliseconds.
methodWe used magnetoencephalography (MEG) to evaluate the cortical network serving temporal perception during a continuous, long-duration (in minutes) time estimation experiment. Briefly, medicated and unmedicated persons with ADHD, and a control group responded each time they estimated 60 s had elapsed for an undisclosed amount of time in two separate MEG sessions. All MEG data were transformed into regional source activity, and subjected to spectral analyses to derive amplitude estimates of gamma-band activity.
resultsCompared to controls, unmedicated patients were less accurate time estimators and had weaker gamma activity in the anterior cingulate, supplementary motor area, and left prefrontal cortex. After medication, these patients exhibited small but significant increases in gamma across these same neural regions and significant improvements in time estimation accuracy, which correlated with the gamma activity increases.
conclusionWe found deficient gamma activity in brain areas known to be crucial for timing functions, which may underlie the day-to-day abnormalities in time perception that are common in ADHD.
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