ArticleEpidemiology and infection2014
What is the price of neglecting parasite groups when assessing the cost of co-infection?
Article in Epidemiology and infection, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Viral Co-Infection in Bats: A Systematic Review.Viruses · 2023Pooled it
- Risk Factors and Coinfection Dynamics of Pathogens in Wild Turkeys (Ecology and evolution · 2026Article
- Unseen Dangers-The Role of Invasive Species in the Spread of Zoonotic Diseases in Europe.Pathogens (Basel, Switzerland) · 2025Article
- Occurrence of multiple infections of rodents with parasites and bacteria in the Sibang Arboretum, Libreville, Gabon.Veterinary world · 2024Article
- Incidence of Chlamydia spp., FIV, FeLV in Free-Roaming Cats in Slovakia.Veterinary medicine (Auckland, N.Z.) · 2024Article
- Co-infection patterns of vector-borne zoonotic pathogens in owned free-ranging dogs in central Chile.Veterinary research communications · 2023Article
- Survey on the prevalence of intestinal parasites in domestic cats (Felis catus Linnaeus, 1758) in central Nepal.Veterinary medicine and science · 2023Article
- Prevalence of Gastrointestinal Parasites in Pigs: A Preliminary Study in Tolon and Kumbungu Districts, Ghana.Journal of parasitology research · 2023Article
- Urban landscape and infection risk in free-roaming cats.Zoonoses and public health · 2022Article
- Gastrointestinal parasites of indigenous pigs (Sus domesticus) in south-central Nepal.Veterinary medicine and science · 2021Article
- Symptomatic and Asymptomatic Protist Infections in Hospital Inpatients in Southwestern China.Pathogens (Basel, Switzerland) · 2021Article
- Coinfections in wildlife: Focus on a neglected aspect of infectious disease epidemiology.PLoS pathogens · 2020Review
- Childhood diarrhoeal diseases in developing countries.Heliyon · 2020Review
- Prevalence of Gastrointestinal Parasites in the Frugivorous and the Insectivorous Bats in Southcentral Nepal.Journal of parasitology research · 2020Article
- Molecular and serological survey of carnivore pathogens in free-roaming domestic cats of rural communities in southern Chile.The Journal of veterinary medical science · 2019Article
- Article
- The physiological cost of male-biased parasitism in a nearly monomorphic mammal.Parasites & vectors · 2017Article
- Impact of co-infections with enteric pathogens on children suffering from acute diarrhea in southwest China.Infectious diseases of poverty · 2016Article
- Case-control study of diarrheal disease etiology in individuals over 5 years in southwest China.Gut pathogens · 2016Article
- Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although co-infection by multiple groups of pathogens is the norm rather than the exception in nature, most research on the effects of pathogens on their hosts has been largely based on a single or few pathogen species. Nevertheless, the health impact of co-occurring infections is evident, and it is important that scientists should consider pathogen communities rather than single relevant pathogen species when assessing the impact of multiple infections. In this work we illustrate the consequences of neglecting different pathogen taxa (viruses, protozoa, helminths, arthropods) in the explanatory power of a set of Partial Least Squares Regression (PLS-R) models used for exploring the impact of co-infections on the body condition of 57 adult feral cats; 71·5% cats were co-infected by ≥3 groups of pathogens. The best two PLS-R models provided a first component based on the combination of helminths, protozoa and viruses, explaining 29·15% of body-condition variability. Statistical models, partially considering the pathogen community, lost between 24% and 94% of their explanatory power for explaining the cost of multiple infections. We believe that in the future, researchers assessing the impact of diseases on host life-history traits should take into account a broad representation of the pathogen community, especially during early assessment of the impact of diseases on host health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.