ArticleJRSM short reports2013
Inappropriate use of proton pump inhibitors among medical inpatients: a questionnaire-based observational study.
Article in JRSM short reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Proton pump inhibitors therapy and risk of Clostridium difficile infection: Systematic review and meta-analysis.World journal of gastroenterology · 2017Pooled it
- Consumption of proton pump inhibitors in outpatients of Gastroenterology Clinics in Khyber Pakhtunkhwa: evidence of inexpedient use.Przeglad gastroenterologiczny · 2024Article
- Assessment of the appropriateness of stress ulcer prophylaxis use and its determinants among admitted surgical patients at Debre Berhan University Hakim Gizaw Hospital, Ethiopia. A hospital-based cross-sectional study.Frontiers in medicine · 2024Article
- Proton Pump Inhibitor Use and Adverse Effects in South Atlantic Hospitals.HCA healthcare journal of medicine · 2023Article
- Feasibility of a pharmacy-led intervention to de-implement non-guideline-concordant proton pump inhibitor use.Implementation science communications · 2021Article
- When does proton pump inhibitor treatment become long term? A scoping review.BMJ open gastroenterology · 2021Article
- Patient Awareness of Reported Adverse Effects Associated with Proton Pump Inhibitors in a Medically Underserved Community.Healthcare (Basel, Switzerland) · 2020Article
- Using a Triple Aim Approach to Implement "Less-is-More Together" and Smarter Medicine Strategies in an Interprofessional Outpatient Setting: Protocol for an Observational Study.JMIR research protocols · 2019Article
- Irrational use of proton pump inhibitors in general practise.Irish journal of medical science · 2019Article
- Guidelines for proton pump inhibitor prescriptions in paediatric intensive care unit.International journal of clinical pharmacy · 2017Observational
- Proton pump inhibitor co-prescription with dual antiplatelet therapy among patients with acute coronary syndrome in Qatar.International journal of clinical pharmacy · 2016Article
- The use of proton pump inhibitors in an Italian hospital: focus on oncologic and critical non-ICU patients.International journal of clinical pharmacy · 2015Observational
- Proton pump inhibitors: Are we still prescribing them without valid indications?The Australasian medical journal · 2014Article
- Deprescribing Proton Pump Inhibitors in an Academic, Primary Care Clinic: Quality Improvement Project.Journal of clinical gastroenterologyArticle
- Prescribing Pattern of Proton Pump Inhibitors in Qatar Rehabilitation Institute: A Retrospective Study.Journal of research in pharmacy practiceArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the appropriateness of proton pump inhibitor (PPI) prescribing by conducting an audit of medical inpatients against recommended guidelines.
designQuestionnaire-based study. All medical wards were audited and different information was documented by patients' medical records review (both hospital visit notes and general practitioner's letters) and short interview, where we asked them to name the clinical reason for using PPI.
settingThis study was carried out in the setting of a regional hospital (537-bed, secondary care referral centre) in Ireland.
participantsThe study participants were all consecutive medical patients admitted to the medical wards at Waterford Regional Hospital, Waterford.
main outcome measuresThe appropriateness of PPI usage in our regional hospital by assessing the level of its prescribing against published guidelines (NICE, 2000).
resultsDuring the audit period, 205 consecutive medical inpatients were assessed. Seventy-nine percent (162 out of 205) of the studied patients were found to be using PPI. For 45% (n = 73) of patients, there was no documentation of valid indication for being on PPI. Overall, 64% of patients were prescribed PPI by hospital doctors, either during their current or previous admissions. We noted that 31% (n = 51) of patients were taking PPI for ≥2 years and another 25% of patients were using PPI for about one year. Only 12% (n = 20) of patients had undergone endoscopy procedures.
conclusionInappropriate use of PPI remains common in hospital practice. The risks of using long-term PPI must be weighed against the benefits.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.