ArticlePloS one2013
Non-additive transcriptional profiles underlie dikaryotic superiority in Pleurotus ostreatus laccase activity.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Article
- Asymmetric mitonuclear interactions trigger transgressive inheritance and mitochondria-dependent heterosis in hybrids of the model systemIMA fungus · 2025Article
- Identification of stable reference genes for qRT-PCR in Stropharia rugosoannulata using mRNA-sequencing data.PloS one · 2025Article
- Exopolysaccharides fromOpen life sciences · 2023Article
- Nuclear-specific gene expression in heterokaryons of the filamentous ascomyceteProceedings. Biological sciences · 2022Article
- Effect of Nutritional Factors and Copper on the Regulation of Laccase Enzyme Production inJournal of fungi (Basel, Switzerland) · 2021Article
- MonokaryoticInternational journal of molecular sciences · 2021Article
- Genetic improvement in3 Biotech · 2019Review
- Laccases: Production, Expression Regulation, and Applications in Pharmaceutical Biodegradation.Frontiers in microbiology · 2017Review
- Validation of Reference Genes for Transcriptional Analyses in Pleurotus ostreatus by Using Reverse Transcription-Quantitative PCR.Applied and environmental microbiology · 2015Article
- Laccase Production and Differential Transcription of Laccase Genes in Cerrena sp. in Response to Metal Ions, Aromatic Compounds, and Nutrients.Frontiers in microbiology · 2015Article
- Genome-wide gene expression patterns in dikaryon of the basidiomycete fungus Pleurotus ostreatus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe basidiomycete Pleurotus ostreatus is an efficient producer of laccases, a group of enzymes appreciated for their use in multiple industrial processes. The aim of this study was to reveal the molecular basis of the superiority of laccase production by dikaryotic strains compared to their parental monokaryons. METHODOLOGY/PRINCIPAL
findingsWe bred and studied a set of dikaryotic strains starting from a meiotic population of monokaryons. We then completely characterised the laccase allelic composition, the laccase gene expression and activity profiles in the dikaryotic strain N001, in two of its meiotic full-sib monokaryons and in the dikaryon formed from their mating. CONCLUSIONS/SIGNIFICANCE: Our results suggested that the dikaryotic superiority observed in laccase activity was due to non-additive transcriptional increases in lacc6 and lacc10 genes. Furthermore, the expression of these genes was divergent in glucose- vs. lignocellulose-supplemented media and was highly correlated to the detected extracellular laccase activity. Moreover, the expression profile of lacc2 in the dikaryotic strains was affected by its allelic composition, indicating a putative single locus heterozygous advantage.
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