ArticlePloS one2013
Anxiety, affect, self-esteem, and stress: mediation and moderation effects on depression.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 128 citations in OpenAlex.
- Trial
- Longitudinal Associations of Active Versus Passive TikTok Use with Depression: A Chain Mediation Model of Autistic Traits and Self-Esteem.Behavioral sciences (Basel, Switzerland) · 2026Article
- Imposter syndrome as mediator and moderator between personality and mental health in Malaysian students.Scientific reports · 2026Article
- Self-esteem and Depression Symptoms among late Adolescents: A Parallel Mediation Model.Journal of child & adolescent trauma · 2025Article
- Article
- Are the effects of stress on antenatal depression mediated by self-esteem and moderated by social support?: a cross-sectional study.Women's health nursing (Seoul, Korea) · 2024Article
- Moderating effect of negative emotion differentiation in chronic stress and fatigue among Chinese employees.Frontiers in psychology · 2024Article
- What do adults with visual impairment mean by well-being? Identifying the building blocks of well-being in the context of visual impairment.Frontiers in psychology · 2024Article
- Testing the effectiveness of the culturally adapted skills training START NOW to reduce mental health problems in adolescent refugees: study protocol for a randomized controlled trial.Frontiers in public health · 2024Article
- Feeling our place in the world: an active inference account of self-esteem.Neuroscience of consciousness · 2024Article
- Statistical analysis of mental influencing factors for anxiety and depression of rural and urban freshmen.Frontiers in public health · 2023Article
- Examining the impact of perceived stress, anxiety, and resilience on depression among medical staff after COVID-19 quarantine: a chain mediation analysis.Frontiers in public health · 2023Observational
- Positive Affect Moderates the Influence of Perceived Stress on the Mental Health of Healthcare Workers during the COVID-19 Pandemic.International journal of environmental research and public health · 2022Article
- Article
- COVID-19 IDD: Findings from a global survey exploring family members' and paid staff's perceptions of the impact of COVID-19 on individuals with intellectual and developmental disabilities (IDD) and their caregivers.HRB open research · 2022Article
- Associations of Maternal-Infant Bonding with Maternal Mental Health, Infant's Characteristics and Socio-Demographical Variables in the Early Postpartum Period: A Cross-Sectional Study.International journal of environmental research and public health · 2021Article
- Paternal Postpartum Bonding and Its Predictors in the Early Postpartum Period: Cross-Sectional Study in a Polish Cohort.Frontiers in psychology · 2021Article
- Influence of Mothers' Habits on Reading Skills and Emotional Intelligence of University Students: Relationships in the Social and Educational Context.Behavioral sciences (Basel, Switzerland) · 2020Article
- Causal Factors of Anxiety and Depression in College Students: Longitudinal Ecological Momentary Assessment and Causal Analysis Using Peter and Clark Momentary Conditional Independence.JMIR mental health · 2020Article
- Prevalence of Prenatal Depression Among Pregnant Women and the Importance of Resilience: A Multi-Site Questionnaire-Based Survey in Mainland China.Frontiers in psychiatry · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMediation analysis investigates whether a variable (i.e., mediator) changes in regard to an independent variable, in turn, affecting a dependent variable. Moderation analysis, on the other hand, investigates whether the statistical interaction between independent variables predict a dependent variable. Although this difference between these two types of analysis is explicit in current literature, there is still confusion with regard to the mediating and moderating effects of different variables on depression. The purpose of this study was to assess the mediating and moderating effects of anxiety, stress, positive affect, and negative affect on depression.
methodsTwo hundred and two university students (males = 93, females = 113) completed questionnaires assessing anxiety, stress, self-esteem, positive and negative affect, and depression. Mediation and moderation analyses were conducted using techniques based on standard multiple regression and hierarchical regression analyses. MAIN
findingsThe results indicated that (i) anxiety partially mediated the effects of both stress and self-esteem upon depression, (ii) that stress partially mediated the effects of anxiety and positive affect upon depression, (iii) that stress completely mediated the effects of self-esteem on depression, and (iv) that there was a significant interaction between stress and negative affect, and between positive affect and negative affect upon depression.
conclusionThe study highlights different research questions that can be investigated depending on whether researchers decide to use the same variables as mediators and/or moderators.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.