ArticleJournal of proteomics & bioinformatics2011
Phosphorylation and Acetylation of Acyl-CoA Synthetase- I.
Article in Journal of proteomics & bioinformatics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Targeting the gut microbiota and lipid metabolism: potential mechanisms of natural products for the treatment of non-alcoholic fatty liver disease.Frontiers in pharmacology · 2025Review
- ACSL1-induced ferroptosis and platinum resistance in ovarian cancer by increasing FSP1 N-myristylation and stability.Cell death discovery · 2023Article
- The Impact of Nicotine along with Oral Contraceptive Exposure on Brain Fatty Acid Metabolism in Female Rats.International journal of molecular sciences · 2022Article
- Influence of Free Fatty Acid Concentrations and Weight Loss on Adipose Tissue Direct Free Fatty Acid Storage Rates.The Journal of clinical endocrinology and metabolism · 2021Article
- Article
- A Comprehensive Proteome and Acetyl-Proteome Atlas Reveals Molecular Mechanisms Adapting to the Physiological Changes From Pre-laying to Peak-Laying Stage in Liver of Hens (Frontiers in veterinary science · 2021Article
- Long-chain acyl-CoA synthetase-1 mediates the palmitic acid-induced inflammatory response in human aortic endothelial cells.American journal of physiology. Endocrinology and metabolism · 2020Article
- Diet and Exercise Training Influence Skeletal Muscle Long-Chain acyl-CoA Synthetases.Medicine and science in sports and exercise · 2020Article
- Evidence for a role of protein phosphorylation in the maintenance of the cnidarian-algal symbiosis.Molecular ecology · 2019Article
- Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways.The Journal of biological chemistry · 2018Article
- Signature molecules expressed differentially in a liver disease stage-specific manner by HIV-1 and HCV co-infection.PloS one · 2018Article
- Circadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome.Cell reports · 2017Article
- Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids.Journal of lipid research · 2017Article
- Directing eicosanoid esterification into phospholipids.Journal of lipid research · 2017Article
- Physiological Consequences of Compartmentalized Acyl-CoA Metabolism.The Journal of biological chemistry · 2015Review
- Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function.Journal of lipid research · 2015Article
- Acyl-CoA metabolism and partitioning.Annual review of nutrition · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Long chain acyl-CoA synthetase 1 (ACSL1) contributes 50 to 90% of total ACSL activity in liver, adipose tissue, and heart and appears to direct the use of long chain fatty acids for energy. Although the functional importance of ACSL1 is becoming clear, little is understood about its post-translational regulation. In order to investigate the post-translational modifications of ACSL1 under different physiological conditions, we overexpressed ACSL1 in hepatocytes, brown adipocytes, and 3T3-L1 differentiated adipocytes, treated these cells with different hormones, and analyzed the resulting phosphorylated and acetylated amino acids by mass spectrometry. We then compared these results to the post-translational modifications observed
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.