ArticleJournal of histotechnology2013
Comparison of standard laminectomy with an optimized ejection method for the removal of spinal cords from rats and mice.
Article in Journal of histotechnology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
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- Topography of the GLP-1/GLP-1 receptor system in the spinal cord of male mice.Scientific reports · 2024Article
- Analysis of translatomic changes in theFrontiers in neurology · 2024Article
- Regional biomechanical characterization of the spinal cord tissue: dynamic mechanical response.Frontiers in bioengineering and biotechnology · 2024Article
- An insight into new glycotherapeutics in glial inflammation: Understanding the role of glycosylation in mitochondrial function and acute to the chronic phases of inflammation.CNS neuroscience & therapeutics · 2023Article
- SpineRacks and SpinalJ for efficient analysis of neurons in a 3D reference atlas of the mouse spinal cord.STAR protocols · 2021Article
- Sensitization of Endothelial Cells to Ionizing Radiation Exacerbates Delayed Radiation Myelopathy in Mice.Radiation research · 2021Article
- Translatomic analysis of regenerating and degenerating spinal motor neurons in injury and ALS.iScience · 2021Article
- Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain.The Journal of experimental medicine · 2021Article
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- The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS.Neurobiology of disease · 2019Article
- Differential Glycosylation Expression in Injured Rat Spinal Cord Treated with Immunosuppressive Drug Cyclosporin-A.ACS omega · 2019Article
- Cell viability in three ex vivo rat models of spinal cord injury.Journal of anatomy · 2019Article
- Monocytes and Monocyte-Derived Antigen-Presenting Cells Have Distinct Gene Signatures in Experimental Model of Multiple Sclerosis.Frontiers in immunology · 2019Article
- Hydraulic Extrusion of the Spinal Cord and Isolation of Dorsal Root Ganglia in Rodents.Journal of visualized experiments : JoVE · 2017Article
- The Use of Ex Vivo Whole-organ Imaging and Quantitative Tissue Histology to Determine the Bio-distribution of Fluorescently Labeled Molecules.Journal of visualized experiments : JoVE · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For researchers seeking to collect spinal cord samples from mice and rats while avoiding acid decalcification, few options are available. Laminectomy is the standard method which yields high quality samples, yet is time consuming and technically difficult. Ejection of the cord from the vertebral column is another technique commonly used; however, the literature suggests that this method can damage the spinal tissues and is typically avoided when histology of samples is the desired endpoint. Here, we describe an optimized method for ejection of spinal cords from rats and mice, and compare histological quality of these samples with those collected via laminectomy. Our results show that ejection can yield high quality spinal cord samples and may be suitable for use as an alternative to laminectomy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.