ReviewInternational forum of allergy & rhinology2013
Chronic rhinosinusitis and sleep: a contemporary review.
Review in International forum of allergy & rhinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Guideline
- Use of low-level laser therapy for patients with chronic rhinosinusitis: a single-blind, sham-controlled clinical trial.Lasers in medical science · 2022Trial
- Analysis of factors associated with electing endoscopic sinus surgery.The Laryngoscope · 2018Trial
- Dyad of pain and depression in chronic rhinosinusitis.International forum of allergy & rhinology · 2016Trial
- Characterization of facial pain associated with chronic rhinosinusitis using validated pain evaluation instruments.International forum of allergy & rhinology · 2015Trial
- Could Dupilumab Improve Sleep Quality in CRSwNP Patients: Myth or Reality? A Systematic Review.Journal of clinical medicine · 2026Review
- Dysbiosis of nasal microbiota associated with hippocampal neuroimmune alterations in a mouse model of eosinophilic chronic rhinosinusitis.Frontiers in immunology · 2026Article
- Nasal Irrigations: A 360-Degree View in Clinical Practice.Medicina (Kaunas, Lithuania) · 2025Review
- Sleep in disease: inflammation and chronic rhinosinusitis.Neurobiology of sleep and circadian rhythms · 2025Article
- Effects of otolaryngological diseases on sleep quality, anxiety, and depression: a multicenter observational study.BMC psychiatry · 2025Observational
- Effect of Hormone Replacement Therapy on Chronic Rhinosinusitis Management.The Laryngoscope · 2024Article
- Snoring in patients with chronic rhinosinusitis after endoscopic sinus surgery.Sleep & breathing = Schlaf & Atmung · 2024Article
- Nasal polyp syndrome: a patient-centred term for CRSwNP by EUFOREA.Frontiers in allergy · 2024Article
- Prevalence and influencing factors of sleep disorders in patients with CRS: a protocol for systematic review and meta-analysis.BMJ open · 2023Article
- The Role of Corticosteroid Nasal Irrigations in the Management of Chronic Rhinosinusitis: A State-of-the-Art Systematic Review.Journal of clinical medicine · 2023Review
- Work productivity and activity impairment in patients with chronic rhinosinusitis undergoing endoscopic sinus surgery-A prospective, multi-institutional study.International forum of allergy & rhinology · 2023Observational
- Managing Chronic Rhinosinusitis with Nasal Polyps in the Elderly: Challenges and Solutions.Clinical interventions in aging · 2022Review
- Vascular permeability in chronic rhinosinusitis enhances accumulation and retention of nanoscale pegylated liposomes.Nanomedicine : nanotechnology, biology, and medicine · 2021Article
- Effect of Obstructive Sleep Apnea on Immunity in Cases of Chronic Rhinosinusitis With Nasal Polyps.Clinical and experimental otorhinolaryngology · 2021Article
- The effects of intermittent hypoxia on human nasal mucosa.Sleep & breathing = Schlaf & Atmung · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPatients with chronic rhinosinusitis (CRS) exhibit centrally mediated behavioral changes commonly referred to as "sickness behavior." Sleep alteration is a component of sickness behavior which is estimated to affect up to 70 million patients annually. Patients with CRS have poor sleep quality, and little is known about the underlying etiology and pathophysiology. This narrative review aims to further organize and present the current knowledge associating sleep and CRS.
methodsA literature search was conducted of the OVID MEDLINE database using key search words including: "chronic rhinosinusitis," "sleep," "sleep disorders," and "sleep dysfunction." Additional keywords "nasal obstruction," "nasal polyp," and "fatigue" were identified and used to further delineate relevant articles.
resultsThe articles that specifically addressed sleep and CRS were dissected and presented as follows: (1) chronic rhinosinusitis and sleep; (2) chronic rhinosinusitis and fatigue; (3) chronic rhinosinusitis, nasal obstruction, and sleep; and (4) pathophysiology of sleep in chronic rhinosinusitis (cytokines in both sleep and chronic rhinosinusitis and their association to the neuroimmune biology of chronic rhinosinusitis).
conclusionPatients with CRS have sleep dysfunction that is associated with their disease severity and overall quality of life. The etiology of sleep dysfunction in CRS is most likely multifactorial. Increasing evidence suggests sleep dysfunction in patients with CRS is partly due to the inflammatory disease process, and sleep physiology in patients with CRS may be actively regulated by the inflammatory component of the disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.