Evidence map›Paper›PMID 24038876›Full record

ArticleChembiochem : a European journal of chemical biology2013

Invaders: Recognition of Double-Stranded DNA by Using Duplexes Modified with Interstrand Zippers of 2'-O-(Pyren-1-yl)methyl-ribonucleotides.

Bradley A Didion, Saswata Karmakar, Dale C Guenther, Sujay P Sau, John P Verstegen, Patrick J Hrdlicka

Abstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bradley A DidionMinitube of America, Inc. PO Box 930187, 419 Venture Ct., Verona, WI 53593 (USA).
Saswata Karmakar
Dale C Guenther
Sujay P Sau
John P Verstegen
Patrick J Hrdlicka

Funding

UNDERGRADUATE COLLEGE OUTREACH PROGRAMP20RR016454 · NCRR · UNIVERSITY OF IDAHO · PI CHASE, JENNIFER R · 2001 to 2011
$35.3M
Invader LNAs as Novel Gene Specific TherapeuticsR01GM088697 · NIGMS · UNIVERSITY OF IDAHO · PI HILL, RODNEY ALLAN, HRDLICKA, PATRICK J. · 2009 to 2011
$519k
HSRD VA PEC 13-001NCRR NIH HHS P20 RR016454NIGMS NIH HHS R01 GM088697
6 · The paper itself

Abstract

The invasion has begun: Invaders are shown to recognize DNA hairpins in cell-free assays and chromosomal DNA during non-denaturing fluorescence in situ hybridization (nd-FISH) experiments. As Invaders are devoid of inherent sequence limitations, many previously inaccessible DNA targets could become accessible to exogenous control with important ramifications for karyotyping, in vivo imaging, and gene regulation.

Indexed as

DNA recognitionFISHfluorescent probesnucleic acid hybridizationoligonucleotides

Identifiers

PMID24038876
PMCPMC3838861

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.